NutriStack
Atenolol and Fish Oil, a synergy.
Fish oil (EPA/DHA) at 2-3 g/day produces small reductions in blood pressure and lowers triglycerides, complementing atenolol's hemodynamic effects in patients with hypertension or cardiovascular disease.
One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.
From the interaction database
What the row says.
Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.
At a glance
- Pair type
- Synergy
- Evidence (highest tier)
- Strong
- Source citations
- 2 sources
- Stack Score effect
- +2 to your Stack Score (per scored synergy row).
- Scope
- Supplement × Prescription
- Last verified
- May 30, 2026
Synergy · Strong evidence
Synergy
What is happening. Fish oil (EPA/DHA) at 2-3 g/day produces small reductions in blood pressure and lowers triglycerides, complementing atenolol's hemodynamic effects in patients with hypertension or cardiovascular disease.
Mechanism. EPA and DHA enhance NO production, reduce vascular inflammation, and improve membrane fluidity. These effects complement atenolol's reduction in heart rate and oxygen demand.
Recommendation. Fish oil at 1-3 g/day is generally compatible with atenolol and may add cardiovascular benefit. Monitor blood pressure when starting, and let your prescriber know if you take high doses (>3 g/day).
Sources (2)
- Zhang X, Ritonja JA, Zhou N, Chen BE, Li X. Omega-3 Polyunsaturated Fatty Acids Intake and Blood Pressure: A Dose-Response Meta-Analysis of Randomized Controlled Trials. J Am Heart Assoc. 2022;11(11):e025071. PMID 35647665
- Morris MC, Sacks F, Rosner B. Does fish oil lower blood pressure? A meta-analysis of controlled trials. Circulation. 1993;88(2):523-33. PMID 8339414
Stack Score
How this pair moves the number.
Effect on the composite score
If both Atenolol and Fish Oil are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.
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