NutriStack
Beta-Alanine and HMB, a synergy.
Beta-alanine combined with HMB has shown additive benefits for lean mass and performance in training studies.
One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.
From the interaction database
What the row says.
Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.
At a glance
- Substances
- Beta-Alanine and HMB
- Pair type
- Synergy
- Evidence (highest tier)
- Moderate
- Source citations
- 1 source
- Stack Score effect
- +2 to your Stack Score (per scored synergy row).
- Scope
- Supplement × Supplement
- Last verified
- May 30, 2026
Synergy · Moderate evidence
Synergy
What is happening. Beta-alanine combined with HMB has shown additive benefits for lean mass and performance in training studies.
Mechanism. Beta-alanine increases muscle carnosine to delay fatigue while HMB attenuates muscle protein breakdown and supports recovery, two distinct mechanisms that support adaptation to training.
Recommendation. May be combined as part of a training regimen without special timing.
Sources (1)
- Kern BD, Robinson TL, Effects of beta-alanine and HMB supplementation on body composition and performance in collegiate wrestlers and football players, Journal of Strength and Conditioning Research, 2011
Stack Score
How this pair moves the number.
Effect on the composite score
If both Beta-Alanine and HMB are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.
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