NutriStack
Calcium and L-Lysine, a synergy.
L-lysine can enhance intestinal calcium absorption and reduce urinary calcium excretion, supporting calcium retention.
One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.
From the interaction database
What the row says.
Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.
At a glance
- Pair type
- Synergy
- Evidence (highest tier)
- Emerging
- Source citations
- 1 source
- Stack Score effect
- +2 to your Stack Score (per scored synergy row).
- Scope
- Supplement × Supplement
- Last verified
- May 30, 2026
Synergy · Emerging evidence
Synergy
What is happening. L-lysine can enhance intestinal calcium absorption and reduce urinary calcium excretion, supporting calcium retention.
Mechanism. Lysine increases gastrointestinal calcium absorption and promotes renal tubular calcium reabsorption, improving net calcium balance.
Recommendation. Can be taken together; lysine may improve the efficiency of calcium uptake when bone or calcium support is the goal.
Sources (1)
- Civitelli R et al, Dietary L-lysine and calcium metabolism in humans, Nutrition, 1992
Stack Score
How this pair moves the number.
Effect on the composite score
If both Calcium and L-Lysine are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.
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