NutriStack
Iron and L-Lysine, a synergy.
Adding L-lysine alongside iron has been associated with improved ferritin levels in some iron-deficient individuals who do not fully respond to iron supplementation alone.
One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.
From the interaction database
What the row says.
Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.
At a glance
- Pair type
- Synergy
- Evidence (highest tier)
- Emerging
- Source citations
- 1 source
- Stack Score effect
- +2 to your Stack Score (per scored synergy row).
- Scope
- Supplement × Supplement
- Last verified
- May 30, 2026
Synergy · Emerging evidence
Synergy
What is happening. Adding L-lysine alongside iron has been associated with improved ferritin levels in some iron-deficient individuals who do not fully respond to iron supplementation alone.
Mechanism. The mechanism is not fully established, but lysine is thought to support intestinal iron absorption and tissue iron utilization, which may raise serum ferritin in lysine-deficient or iron-resistant states.
Recommendation. Lysine may be a useful adjunct alongside iron in poor responders; continue standard iron dosing and monitor ferritin.
Sources (1)
- Rushton DH et al, Lysine and iron in the treatment of women with hair loss and low ferritin, Clinical and Experimental Dermatology, 2002
Stack Score
How this pair moves the number.
Effect on the composite score
If both Iron and L-Lysine are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.
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