Interaction databaseSupplement × SupplementReviewed May 2026

Calcium and Psyllium Husk, timing-sensitive.

Psyllium can bind calcium and accelerate intestinal transit, modestly reducing calcium absorption when co-administered.

One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
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At a glance

Substances
Calcium and Psyllium Husk
Pair type
Timing Sensitive
Evidence (highest tier)
Emerging
Source citations
2 sources
Stack Score effect
−5 to your Stack Score (per scored timing-sensitive row).
Scope
Supplement × Supplement
Last verified
May 30, 2026

Timing Sensitive · Emerging evidence

Timing Sensitive

What is happening. Psyllium can bind calcium and accelerate intestinal transit, modestly reducing calcium absorption when co-administered.

Mechanism. The viscous fiber gel sequesters calcium cations and shortens the residence time in the absorptive segments of the gut, lowering net calcium uptake.

Recommendation. Take calcium supplements at least 2 hours away from psyllium. Split doses across the day if both are needed.

Minimum separation. 2 hours

Sources (2)
  1. Anderson JW et al, Health benefits of dietary fiber, Nutrition Reviews, 2009
  2. Fernandez-Banares F, Nutritional care of the patient with constipation, Best Practice and Research Clinical Gastroenterology, 2006. Nutritional care of the patient with constipation. Best Pract Res Clin Gastroenterol. 2006. PMID 16782530

Stack Score

How this pair moves the number.

Effect on the composite score

If both Calcium and Psyllium Husk are in the same stack, this pair applies −5 to your Stack Score (per scored timing-sensitive row).

The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.

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