NutriStack
Chromium and Magnesium Glycinate, a synergy.
Chromium and magnesium each support insulin signaling, so adequate status of both is associated with better insulin sensitivity than low status of either.
One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.
From the interaction database
What the row says.
Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.
At a glance
- Substances
- Chromium and Magnesium Glycinate
- Pair type
- Synergy
- Evidence (highest tier)
- Emerging
- Source citations
- 2 sources
- Stack Score effect
- +2 to your Stack Score (per scored synergy row).
- Scope
- Supplement × Supplement
- Last verified
- May 30, 2026
Synergy · Emerging evidence
Synergy
What is happening. Chromium and magnesium each support insulin signaling, so adequate status of both is associated with better insulin sensitivity than low status of either.
Mechanism. Magnesium is a cofactor for the tyrosine kinase activity of the insulin receptor and downstream glucose-handling enzymes, while chromium enhances insulin receptor responsiveness via chromodulin, so adequacy of both supports the same insulin-signaling pathway from different points.
Recommendation. Reasonable to take together for metabolic support. No timing restriction is needed.
Stack Score
How this pair moves the number.
Effect on the composite score
If both Chromium and Magnesium Glycinate are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.
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