Interaction databaseSupplement × SupplementReviewed May 2026

Coenzyme Q10 and Cordyceps, a synergy.

Both support mitochondrial energy production. Cordyceps increases ATP synthesis; CoQ10 is essential for the electron transport chain.

One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.

Sourcing standards·Evidence tiers

From the interaction database

What the row says.

Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.

At a glance

Substances
Coenzyme Q10 and Cordyceps
Pair type
Synergy
Evidence (highest tier)
Emerging
Source citations
1 source
Stack Score effect
+2 to your Stack Score (per scored synergy row).
Scope
Supplement × Supplement
Last verified
May 30, 2026

Synergy · Emerging evidence

Synergy

What is happening. Both support mitochondrial energy production. Cordyceps increases ATP synthesis; CoQ10 is essential for the electron transport chain.

Mechanism. Cordycepin and adenosine from cordyceps enhance mitochondrial biogenesis via AMPK/PGC-1α. CoQ10 shuttles electrons in Complex I→III of the ETC. Synergistic mitochondrial support.

Recommendation. Combine for enhanced cellular energy, exercise performance, and mitochondrial support.

Sources (1)
  1. Hirsch KR et al. Cordyceps militaris improves tolerance to high-intensity exercise. J Diet Suppl. 2017

Stack Score

How this pair moves the number.

Effect on the composite score

If both Coenzyme Q10 and Cordyceps are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).

The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.

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