Supplement × Supplement·a caution·Insufficient evidence
Creatine can increase body water and scale weight, while tesamorelin can cause edema or fluid-related symptoms.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
What is happening. Creatine can increase body water and scale weight, while tesamorelin can cause edema or fluid-related symptoms.
Mechanism. Creatine-related intracellular water shifts plus GH-axis fluid retention.
Recommendation. Differentiate expected creatine water weight from new edema, numbness, carpal tunnel symptoms, or joint pain.
Effect on the composite score
If both Creatine and Tesamorelin are in the same stack, this pair applies −5 to your Stack Score (per scored caution row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
Every claim on this page is cited. PMIDs link straight to PubMed.
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