Interaction databaseSupplement × SupplementReviewed May 2026

D-Aspartic Acid and Magnesium Glycinate, a synergy.

Magnesium status is linked to testosterone, so magnesium glycinate may complement D-aspartic acid in supporting the androgen axis, especially where magnesium intake is suboptimal.

One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.

Sourcing standards·Evidence tiers

From the interaction database

What the row says.

Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.

At a glance

Substances
D-Aspartic Acid and Magnesium Glycinate
Pair type
Synergy
Evidence (highest tier)
Emerging
Source citations
2 sources
Stack Score effect
+2 to your Stack Score (per scored synergy row).
Scope
Supplement × Supplement
Last verified
May 30, 2026

Synergy · Emerging evidence

Synergy

What is happening. Magnesium status is linked to testosterone, so magnesium glycinate may complement D-aspartic acid in supporting the androgen axis, especially where magnesium intake is suboptimal.

Mechanism. Magnesium reduces binding of testosterone to sex hormone binding globulin and supports bioavailable testosterone, while D-aspartic acid acts centrally to stimulate hormone release, giving complementary effects on the axis.

Recommendation. Reasonable to combine. Magnesium glycinate is well tolerated; benefit on testosterone is most likely with low baseline magnesium.

Sources (2)
  1. Maggio M et al., Magnesium and anabolic hormones in older men, International Journal of Andrology, 2011
  2. Cinar V et al., Effects of magnesium supplementation on testosterone levels of athletes and sedentary subjects at rest and after exhaustion, Biological Trace Element Research, 2011

Stack Score

How this pair moves the number.

Effect on the composite score

If both D-Aspartic Acid and Magnesium Glycinate are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).

The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.

Check your full routine

One pair was the worked example. NutriStack runs every pair in your stack at once.

Drop in your supplements and prescriptions and the public database surfaces every interaction, synergy, timing rule, and contraindication, every one linked to its primary source.

NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.