From the databaseWhat the row says.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
Pair type
Timing Sensitive
Scope
Supplement × Supplement
Last verified
June 4, 2026
Timing SensitiveEmerging evidence
What is happening. Fisetin is fat-soluble and poorly absorbed; taking it alongside an omega-3 fish oil softgel provides a convenient dietary-fat carrier to support absorption.
Mechanism. Co-ingestion with dietary lipids increases solubilization and absorption of poorly water-soluble flavonoids like fisetin.
Recommendation. Take fisetin together with fish oil or another fat-containing meal to improve uptake.
Stack Score
How it moves the number.
Effect on the composite score
If both Fisetin and Fish Oil are in the same stack, this pair applies −5 to your Stack Score (per scored timing-sensitive row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
SourcesSources, by evidence tier.
Every claim on this page is cited. PMIDs link straight to PubMed.
Reference material
1- 1Khan N et al. Therapeutic potential of dietary flavonoid fisetin: A comprehensive review. Antioxid Redox Signal. 2013.Needs sourceNo link