NutriStack
Ginkgo Biloba and Holy Basil/Tulsi, a caution.
Holy basil and ginkgo biloba both reduce platelet aggregation, so taking them together can additively impair clotting and theoretically raise bleeding risk, particularly around surgery, dental procedures, or in anyone already taking antiplatelet or anticoagulant agents.
One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.
From the interaction database
What the row says.
Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.
At a glance
- Substances
- Ginkgo Biloba and Holy Basil/Tulsi
- Pair type
- Caution
- Evidence (highest tier)
- Emerging
- Source citations
- 2 sources
- Stack Score effect
- −5 to your Stack Score (per scored caution row).
- Scope
- Supplement × Supplement
- Last verified
- May 30, 2026
Caution · Emerging evidence
Caution
What is happening. Holy basil and ginkgo biloba both reduce platelet aggregation, so taking them together can additively impair clotting and theoretically raise bleeding risk, particularly around surgery, dental procedures, or in anyone already taking antiplatelet or anticoagulant agents.
Mechanism. Both botanicals inhibit platelet aggregation. Holy basil constituents (notably eugenol and related compounds) reduce platelet aggregation and show antiplatelet activity in preclinical models, while ginkgo biloba (via ginkgolides, especially the platelet-activating-factor antagonist ginkgolide B) inhibits arachidonic-acid-, ADP-, collagen-, and PAF-induced platelet aggregation. Combined use produces an additive reduction in platelet function.
Recommendation. For healthy adults not on blood thinners this combination is usually tolerated, but treat it with bleeding awareness. Avoid combining if you take anticoagulant or antiplatelet medication without clinician oversight, and stop both supplements at least 1 to 2 weeks before any scheduled surgery or invasive dental work. Report unusual bruising, nosebleeds, or prolonged bleeding from minor cuts. Typical ginkgo doses are 120 to 240 mg/day standardized extract; keep holy basil to label dosing and do not stack additional antiplatelet supplements on top.
Stack Score
How this pair moves the number.
Effect on the composite score
If both Ginkgo Biloba and Holy Basil/Tulsi are in the same stack, this pair applies −5 to your Stack Score (per scored caution row).
The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.
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