NutriStack
Ashwagandha and Holy Basil/Tulsi, a synergy.
Both are adaptogenic herbs with stress-modulating effects; combined use is common in HPA-axis support stacks.
One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.
From the interaction database
What the row says.
Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.
At a glance
- Substances
- Ashwagandha and Holy Basil/Tulsi
- Pair type
- Synergy
- Evidence (highest tier)
- Emerging
- Source citations
- 1 source
- Stack Score effect
- +2 to your Stack Score (per scored synergy row).
- Scope
- Supplement × Supplement
- Last verified
- May 30, 2026
Synergy · Emerging evidence
Synergy
What is happening. Both are adaptogenic herbs with stress-modulating effects; combined use is common in HPA-axis support stacks.
Mechanism. Both attenuate cortisol responses and modulate stress reactivity via complementary mechanisms (holy basil targets cortisol and glucose; ashwagandha targets cortisol and androgens).
Recommendation. Common doses: holy basil 300 to 600 mg plus ashwagandha 300 to 600 mg per day. Effect builds over 4 to 8 weeks.
Sources (1)
- Cohen MM. Tulsi - Ocimum sanctum: A herb for all reasons. J Ayurveda Integr Med. 2014
Stack Score
How this pair moves the number.
Effect on the composite score
If both Ashwagandha and Holy Basil/Tulsi are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.
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