NSTK · 01.2026Independent supplement reference
NutriStack
Edition 1.0Updated August 1, 2026

Supplement × Supplement·Evidence index

Ashwagandha and Panax Ginseng: what the published research says

PubMed indexes 5 records that name Ashwagandha and Panax Ginseng together, either in the title or in an interaction, co-administration, or pharmacokinetic context. Each one is listed below with its study design and, where the abstract states one, the authors’ own conclusion, quoted and linked. This page reports that literature. It does not tell you whether to combine them.

Read this first

An evidence index, not guidance.

Every statement below is attributed to a named, dated, linked source.

This page lists published research relevant to Ashwagandha and Panax Ginseng. It deliberately does not state whether the combination is safe, whether it interacts, in which direction, at what dose, or how far apart to take them.

The research

5 studies naming Ashwagandha and Panax Ginseng.

Strongest relevance first: papers naming both substances in the title, then human trials and systematic reviews.

Comparative root protein profiles of Korean ginseng (Panax ginseng) and Indian ginseng (Withania somnifera).

The American journal of Chinese medicine · 2012 · PMID 22298459

Comparative Study

“The results of this study, to our knowledge, are the first to provide a reference 2-DE map for the W. somnifera root proteome, and will aid in the understanding of the expression and functions of proteins in the roots of Korean ginseng and Indian ginseng.”

Nagappan et al. · From the abstract

Names both Ashwagandha and Panax Ginseng in its title.

Effect of Asian ginseng, Siberian ginseng, and Indian ayurvedic medicine Ashwagandha on serum digoxin measurement by Digoxin III, a new digoxin immunoassay.

Journal of clinical laboratory analysis · 2008 · PMID 18623124

Human subjects

“For example, we observed 48.2% (1.63 ng/ml digoxin) increase in digoxin concentration when an aliquot of Digoxin pool 1 (1.10 ng/ml digoxin) was supplemented with 50 microl of Asian ginseng extract (Brand 2). Measuring free digoxin does not eliminate the modest interferences of these herbal supplements in serum digoxin measurement by the Digoxin III assay.”

Dasgupta et al. · From the abstract

Names both Ashwagandha and Panax Ginseng in its title.

Adrenocorticosterone alterations in male, albino mice treated with Trichopus zeylanicus, Withania somnifera and Panax ginseng preparations.

Phytotherapy research : PTR · 2000 · PMID 10685111

Animal study

“The treatments increased the corticosterone levels in all the groups. The physical endurance (increased survival time) of swimming mice also increased in all the treated groups, except in the group treated with Withania somnifera powder (500 mg/kg, p.o.).”

Singh et al. · From the abstract

Names both Ashwagandha and Panax Ginseng in its title.

Limitations

What this evidence cannot tell you.

Search-based evidence indexes have real limits, and it is worth being explicit about them:

NutriStack

Track what you actually take.

NutriStack is a free iPhone app for organising a supplement routine: what you take, when, and what the published record says about it. Its exploratory interaction checker covers Ashwagandha, Panax Ginseng, and several hundred other substances.

The checker is a research and organisation tool, not a clinical decision aid, and its per-pair assessments are excluded from search until they pass claim-level review.

NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.