From the databaseWhat the row says.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
Scope
Supplement × Prescription
Last verified
June 4, 2026
CautionEmerging evidence
What is happening. Vilazodone can increase bleeding risk through platelet serotonin effects; ginkgo may also increase bleeding tendency in susceptible patients.
Mechanism. Serotonergic antidepressants reduce platelet serotonin uptake, while ginkgo constituents may affect platelet activating factor and hemostasis.
Recommendation. Use cautiously and avoid the combination around surgery or when taking anticoagulants, antiplatelets, or frequent NSAIDs.
Stack Score
How it moves the number.
Effect on the composite score
If both Ginkgo Biloba and Vilazodone are in the same stack, this pair applies −5 to your Stack Score (per scored caution row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
SourcesSources, by evidence tier.
Every claim on this page is cited. PMIDs link straight to PubMed.
Reference material
1- 1U.S. National Library of Medicine. Vilazodone hydrochloride tablets US Prescribing Information. 2025.Needs sourceNo link