Interaction databaseSupplement × SupplementReviewed May 2026

Ginkgo Biloba and Vitamin K1, a caution.

Ginkgo's antiplatelet activity can mildly counter vitamin K1's pro-coagulant role; relevant for warfarin patients managing INR through K1 intake.

One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.

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What the row says.

Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.

At a glance

Substances
Ginkgo Biloba and Vitamin K1
Pair type
Caution
Evidence (highest tier)
Moderate
Source citations
1 source
Stack Score effect
−5 to your Stack Score (per scored caution row).
Scope
Supplement × Supplement
Last verified
May 30, 2026

Caution · Moderate evidence

Caution

What is happening. Ginkgo's antiplatelet activity can mildly counter vitamin K1's pro-coagulant role; relevant for warfarin patients managing INR through K1 intake.

Mechanism. Vitamin K1 enables clotting factor activation; ginkgo inhibits platelet aggregation. Net effect on PT/INR is small but adds variability.

Recommendation. For warfarin patients, keep both vitamin K1 intake and ginkgo dose stable. Monitor INR closely if either changes.

Sources (1)
  1. Engelsen J et al. Effect of coenzyme Q10 and Ginkgo biloba on warfarin dosage in stable, long-term warfarin treated outpatients. A randomised, double blind, placebo-crossover trial. Thromb Haemost. 2002. PMID 12083489

Stack Score

How this pair moves the number.

Effect on the composite score

If both Ginkgo Biloba and Vitamin K1 are in the same stack, this pair applies −5 to your Stack Score (per scored caution row).

The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.

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