From the databaseWhat the row says.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
Scope
Supplement × Supplement
Last verified
June 4, 2026
CautionInsufficient evidence
What is happening. Weight-loss supplement stacking can increase adverse-effect burden while efficacy remains unproven.
Mechanism. Overlapping weight-loss marketing with different safety liabilities.
Recommendation. Avoid multi-agent weight-loss stacks, especially with liver disease, anxiety, or hypertension.
Stack Score
How it moves the number.
Effect on the composite score
If both Green Tea Extract and HGH Fragment 176-191 are in the same stack, this pair applies −5 to your Stack Score (per scored caution row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
SourcesSources, by evidence tier.
Every claim on this page is cited. PMIDs link straight to PubMed.
Reference material
1- 1Heffernan MA et al. AOD9604 animal lipid metabolism. Endocrinology. 2001.Needs sourceNo link