NutriStack
Green Tea Extract and Quercetin, a synergy.
Quercetin may raise plasma levels of green tea catechins by slowing their breakdown, and the two polyphenols provide additive antioxidant and anti-inflammatory activity.
One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.
From the interaction database
What the row says.
Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.
At a glance
- Substances
- Green Tea Extract and Quercetin
- Pair type
- Synergy
- Evidence (highest tier)
- Emerging
- Source citations
- 2 sources
- Stack Score effect
- +2 to your Stack Score (per scored synergy row).
- Scope
- Supplement × Supplement
- Last verified
- May 30, 2026
Synergy · Emerging evidence
Synergy
What is happening. Quercetin may raise plasma levels of green tea catechins by slowing their breakdown, and the two polyphenols provide additive antioxidant and anti-inflammatory activity.
Mechanism. Quercetin can inhibit catechol-O-methyltransferase and efflux transporters that normally methylate and remove EGCG, increasing catechin exposure in preclinical models, and both compounds scavenge free radicals and inhibit NF-kB signaling.
Recommendation. Reasonable to take together for antioxidant support, with no special timing needed. Avoid stacking very high doses of multiple polyphenols if you have liver concerns.
Sources (2)
- Wang P, Heber D, Henning SM. Quercetin increased the antiproliferative activity of green tea polyphenol EGCG in prostate cancer cells. Nutrition and Cancer. 2012
- Lambert JD, Sang S, Yang CS. Biotransformation of green tea polyphenols and the biological activities of those metabolites. Molecular Pharmaceutics. 2007
Stack Score
How this pair moves the number.
Effect on the composite score
If both Green Tea Extract and Quercetin are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.
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