From the databaseWhat the row says.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
Scope
Supplement × Prescription
Last verified
June 4, 2026
CautionEmerging evidence
What is happening. Concentrated green tea extract has been associated with liver injury, which can complicate use of hepatotoxic drugs such as Voriconazole.
Mechanism. This is an additive hepatic safety concern rather than a proven pharmacokinetic interaction.
Recommendation. Avoid high-dose green tea extract during therapy or use only with clinician review, especially if liver enzymes are abnormal or symptoms of hepatitis occur.
Stack Score
How it moves the number.
Effect on the composite score
If both Green Tea Extract and Voriconazole are in the same stack, this pair applies −5 to your Stack Score (per scored caution row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
SourcesSources, by evidence tier.
Every claim on this page is cited. PMIDs link straight to PubMed.
Reference material
1- 1National Institutes of Health LiverTox. Green Tea. 2024.Needs sourceNo link