NutriStack
Magnesium Malate and Vitamin B6, a synergy.
Vitamin B6 increases intracellular magnesium accumulation. Magnesium is required for B6 activation to its coenzyme form PLP.
One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.
From the interaction database
What the row says.
Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.
At a glance
- Substances
- Magnesium Malate and Vitamin B6
- Pair type
- Synergy
- Evidence (highest tier)
- Moderate
- Source citations
- 1 source
- Stack Score effect
- +2 to your Stack Score (per scored synergy row).
- Scope
- Supplement × Supplement
- Last verified
- May 30, 2026
Synergy · Moderate evidence
Synergy
What is happening. Vitamin B6 increases intracellular magnesium accumulation. Magnesium is required for B6 activation to its coenzyme form PLP.
Mechanism. Pyridoxine (B6) facilitates magnesium transport into cells. Magnesium is a cofactor for pyridoxal kinase, which converts B6 to its active form pyridoxal-5-phosphate (PLP).
Recommendation. Take together for enhanced mutual absorption and utilization.
Sources (1)
- Pouteau E et al. Superiority of magnesium and vitamin B6 over magnesium alone. Magnes Res. 2018
Stack Score
How this pair moves the number.
Effect on the composite score
If both Magnesium Malate and Vitamin B6 are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.
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