Supplement × Supplement·a synergy·Moderate evidence

Peppermint Oil (Enteric-Coated) + Psyllium Husk

Synergy Moderate evidence

Psyllium and peppermint oil may address different IBS symptom drivers: stool form and spasm.

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Pair type
Synergy
Evidence
Moderate
Source citations
1
Scope
Supplement × Supplement
Last verified
June 4, 2026
SynergyModerate evidence

What is happening. Psyllium and peppermint oil may address different IBS symptom drivers: stool form and spasm.

Mechanism. Fiber bulking plus smooth-muscle relaxation may be complementary.

Recommendation. Use psyllium with plenty of water and peppermint oil before meals; separate if capsules seem delayed or symptoms worsen.

Stack Score

How it moves the number.

Effect on the composite score

If both Peppermint Oil (Enteric-Coated) and Psyllium Husk are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).

The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.

Sources

Sources, by evidence tier.

Every claim on this page is cited. PMIDs link straight to PubMed.

Reference material

1
  • 1Lacy BE et al. ACG IBS guideline. American Journal of Gastroenterology. 2021.Needs sourceNo link

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