From the databaseWhat the row says.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
Scope
Supplement × Supplement
Last verified
June 4, 2026
CautionInsufficient evidence
What is happening. Magnesium can loosen stool while peppermint oil relaxes smooth muscle, potentially increasing diarrhea or urgency in sensitive users.
Mechanism. Additive GI motility and smooth-muscle effects.
Recommendation. Adjust magnesium dose if stools loosen or cramping changes.
Stack Score
How it moves the number.
Effect on the composite score
If both Magnesium Glycinate and Peppermint Oil (Enteric-Coated) are in the same stack, this pair applies −5 to your Stack Score (per scored caution row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
SourcesSources, by evidence tier.
Every claim on this page is cited. PMIDs link straight to PubMed.
Reference material
1- 1Alammar N et al. Peppermint oil IBS meta-analysis. BMC Complementary and Alternative Medicine. 2019.Needs sourceNo link