From the databaseWhat the row says.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
Pair type
Timing Sensitive
Scope
Supplement × Prescription
Last verified
June 4, 2026
Timing SensitiveEmerging evidence
What is happening. Large doses of soluble fiber can reduce or delay absorption of some oral drugs and may make raloxifene exposure less predictable.
Mechanism. Fiber gel formation can delay drug dissolution and intestinal contact.
Recommendation. Separate psyllium from raloxifene by at least 2 hours if both are used daily.
TimingTiming & separation.
Space the doses apart by at least this window to avoid the conflict.
Stack Score
How it moves the number.
Effect on the composite score
If both Psyllium Husk and Raloxifene are in the same stack, this pair applies −5 to your Stack Score (per scored timing-sensitive row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
SourcesSources, by evidence tier.
Every claim on this page is cited. PMIDs link straight to PubMed.
Reference material
1- 1U.S. National Library of Medicine. Raloxifene Hydrochloride Tablets US Prescribing Information. 2026.Needs sourceNo link