Medication·Interactions & depletion·Reviewed June 9, 2026
Oxcarbazepine interactions.
Oxcarbazepine has 4 documented interactions in the NutriStack database. Prolonged use is also associated with lower Sodium. The full interaction list, depletion table, and replacement suggestions are below. None of this is a substitute for your prescriber's advice.
Oxcarbazepine at a glance.
A quick, data-grounded summary. The full tables are below.
Oxcarbazepine has 4 documented interactions in the NutriStack database. Prolonged use is also associated with lower Sodium. The full interaction list, depletion table, and replacement suggestions are below. None of this is a substitute for your prescriber's advice.
Substances that interact with oxcarbazepine.
Every supplement and medication in the NutriStack database with a documented interaction with this drug, highest-severity first. Open any pair for the mechanism and sources.
| Substance | Interaction | What happens |
|---|---|---|
| Ashwagandha | Caution | Ashwagandha may cause sedation and could add to oxcarbazepine CNS effects. |
| Ginkgo Biloba | Caution | Ginkgo has seizure case reports and is undesirable in patients taking antiseizure medication. |
| Melatonin | Caution | Melatonin may add to oxcarbazepine-related dizziness and somnolence. |
| St. John's Wort | Caution | St. John's Wort is an inducer of CYP3A4 and P-glycoprotein. Oxcarbazepine also induces CYP3A4, so the combination can amplify interaction burden for... |
What oxcarbazepine can deplete.
Nutrients this medication is associated with lowering over time, with the mechanism, a suggested replacement where one applies, and the biomarker to monitor. Discuss any replacement with your prescriber first.
| Nutrient | Severity | How it happens | Replace with | Monitor |
|---|---|---|---|---|
| Sodium | Significant | Oxcarbazepine can cause dilutional hyponatremia through antidiuretic hormone-like effects and impaired free-water handling, lowering serum sodium... | Medical sodium correction or fluid management only under clinician supervision | Serum sodium |
The full oxcarbazepine profile.
Uses, typical dosing, side effects, and the cited evidence for this medication.
Common oxcarbazepine questions.
Quick answers drawn from the tables above.
What interacts with Oxcarbazepine?
In the NutriStack database, Oxcarbazepine has 4 documented interactions. The most notable include Ashwagandha, Ginkgo Biloba, Melatonin, and St. John's Wort. Check any specific combination before taking it and confirm with your prescriber.
Does Oxcarbazepine deplete any nutrients?
Oxcarbazepine is associated with lowering Sodium with prolonged use. Useful biomarkers to monitor include Serum sodium. Ask your prescriber before adding any replacement supplement.
Is it safe to take Ashwagandha with Oxcarbazepine?
NutriStack classifies the Ashwagandha and Oxcarbazepine pairing as caution: Ashwagandha may cause sedation and could add to oxcarbazepine CNS effects. Use cautiously, especially during dose changes or if dizziness is present. Always confirm with your prescriber.
Check your whole stack
See how oxcarbazepine fits your supplements.
NutriStack screens your full routine for interactions and depletions, and updates the moment you change it.