Medication·Interactions & depletion·Reviewed June 9, 2026
Quinapril interactions.
Quinapril has 4 documented interactions in the NutriStack database, including 1 flagged to avoid or as a serious conflict. Prolonged use is also associated with lower Zinc. The full interaction list, depletion table, and replacement suggestions are below. None of this is a substitute for your prescriber's advice.
Quinapril at a glance.
A quick, data-grounded summary. The full tables are below.
Quinapril has 4 documented interactions in the NutriStack database, including 1 flagged to avoid or as a serious conflict. Prolonged use is also associated with lower Zinc. The full interaction list, depletion table, and replacement suggestions are below. None of this is a substitute for your prescriber's advice.
Substances that interact with quinapril.
Every supplement and medication in the NutriStack database with a documented interaction with this drug, highest-severity first. Open any pair for the mechanism and sources.
| Substance | Interaction | What happens |
|---|---|---|
| Potassium | Conflict | ACE inhibitors such as quinapril reduce aldosterone secretion, which decreases urinary potassium excretion and raises serum potassium. Adding... |
| L-Citrulline | Caution | L-Citrulline may add to the blood-pressure-lowering effect of Quinapril. |
| Magnesium Glycinate | Caution | Magnesium Glycinate may add to the blood-pressure-lowering effect of Quinapril. |
| Iron | Timing Sensitive | Oral iron salts can chelate ACE inhibitors in the gastrointestinal tract, and quinapril's magnesium carbonate formulation may also reduce iron... |
What quinapril can deplete.
Nutrients this medication is associated with lowering over time, with the mechanism, a suggested replacement where one applies, and the biomarker to monitor. Discuss any replacement with your prescriber first.
| Nutrient | Severity | How it happens | Replace with | Monitor |
|---|---|---|---|---|
| Zinc | Mild | ACE inhibitors, including quinapril, contain or form sulfhydryl-related chelating chemistry and increase urinary zinc excretion, which over time can... | Zinc | Serum or plasma zinc |
The full quinapril profile.
Uses, typical dosing, side effects, and the cited evidence for this medication.
Common quinapril questions.
Quick answers drawn from the tables above.
What interacts with Quinapril?
In the NutriStack database, Quinapril has 4 documented interactions. The most notable include Potassium, L-Citrulline, Magnesium Glycinate, and Iron. Check any specific combination before taking it and confirm with your prescriber.
Which substances should I avoid with Quinapril?
Quinapril is flagged against 1 substance in the database, including Potassium. These pairings carry a higher risk and should be reviewed with a clinician before combining.
Does Quinapril deplete any nutrients?
Quinapril is associated with lowering Zinc with prolonged use. Useful biomarkers to monitor include Serum or plasma zinc. Ask your prescriber before adding any replacement supplement.
Is it safe to take Potassium with Quinapril?
NutriStack classifies the Potassium and Quinapril pairing as conflict: ACE inhibitors such as quinapril reduce aldosterone secretion, which decreases urinary potassium excretion and raises serum potassium. Adding supplemental potassium (or... Avoid routine potassium supplements and potassium-containing salt substitutes while taking quinapril unless prescribed and monitored. If... Always confirm with your prescriber.
Check your whole stack
See how quinapril fits your supplements.
NutriStack screens your full routine for interactions and depletions, and updates the moment you change it.