Alcohol
Other ·Exploratory record · not publication-reviewed ·Updated July 13, 2026
Alcohol is not supported by NutriStack. Safety information only.
Exploratory record, not a reviewed medical publication.
See the editorial and medical-review policies for the publication gate.
This safety record covers a controlled, investigational, or otherwise out-of-scope substance. It remains available for reference, but it is not part of NutriStack's public supplement publication set.
What the research says.
A quick, data-only summary. The full evidence, dosing, and sources are below.
Alcohol is an other. NutriStack rates the overall evidence as insufficient. This profile indexes 15 sources.
The bottom line
Evidence rating insufficient. 15 sources indexed (2017–2026), with 0 interaction records on file.
Dosing & protocol.
What it actually costs.
Real-world pricing across three quality tiers. Assumes Not recommended / non-supplement.
No effective supplement dose exists. Cost is intentionally not modeled for this recreational substance. Updated 2026-05-28.
The same dose, as food.
How much you'd eat to match a supplemental dose.
Alcohol is not a nutrient supplement and has no diet-first equivalent for wellness dosing.
Full safety detail.
Side effects
- Impaired judgment and coordination
- Sedation
- Nausea and vomiting
- Sleep disruption
- Tolerance and withdrawal with repeated use
- Liver injury
- Higher cancer risk with regular use
Sources, by evidence tier.
Numbered references. Citations throughout the page link here.
Meta-analyses & systematic reviews
13- 1Pharmacological Strategies for the Management of Severe Alcohol-associated Hepatitis: A Systematic Review and Meta-AnalysisPMIDIslam AH, Alvizuri C, Desalegn H et al. · Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2026
Islam AH, Alvizuri C, Desalegn H et al.. Pharmacological Strategies for the Management of Severe Alcohol-associated Hepatitis: A Systematic Review and Meta-Analysis. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 2026
- 2The effect of alcohol on subsequent sleep in healthy adults: A systematic review and meta-analysisPMIDGardiner C, Weakley J, Burke LM et al. · Sleep medicine reviews · 2025
Gardiner C, Weakley J, Burke LM et al.. The effect of alcohol on subsequent sleep in healthy adults: A systematic review and meta-analysis. Sleep medicine reviews. 2025
- 3Efficacy and safety of alcohol reduction pharmacotherapy according to treatment duration in patients with alcohol dependence or alcohol use disorder: A systematic review and network meta-analysisPMIDKotake K, Hosokawa T, Tanaka M et al. · Addiction (Abingdon, England) · 2024
Kotake K, Hosokawa T, Tanaka M et al.. Efficacy and safety of alcohol reduction pharmacotherapy according to treatment duration in patients with alcohol dependence or alcohol use disorder: A systematic review and network meta-analysis. Addiction (Abingdon, England). 2024
- 4Phenobarbital treatment of alcohol withdrawal in the emergency department: A systematic review and meta-analysisPMIDLee CM, Dillon DG, Tahir PM et al. · Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2024
Lee CM, Dillon DG, Tahir PM et al.. Phenobarbital treatment of alcohol withdrawal in the emergency department: A systematic review and meta-analysis. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine. 2024
- 5Disruption of circadian rhythms promotes alcohol use: a systematic reviewPMIDNelson MJ, Soliman PS, Rhew R et al. · Alcohol and alcoholism (Oxford, Oxfordshire) · 2024
Nelson MJ, Soliman PS, Rhew R et al.. Disruption of circadian rhythms promotes alcohol use: a systematic review. Alcohol and alcoholism (Oxford, Oxfordshire). 2024
- 6Transdiagnosis of alcohol use and psychopathologies: A systematic reviewPMIDde Aguiar ACL, Bloc LG · Addictive behaviors reports · 2024
de Aguiar ACL, Bloc LG. Transdiagnosis of alcohol use and psychopathologies: A systematic review. Addictive behaviors reports. 2024
- 7Alcohol Intake and Risk of Hypertension: A Systematic Review and Dose-Response Meta-Analysis of Nonexperimental Cohort StudiesPMIDCecchini M, Filippini T, Whelton PK et al. · Hypertension (Dallas, Tex. : 1979) · 2024
Cecchini M, Filippini T, Whelton PK et al.. Alcohol Intake and Risk of Hypertension: A Systematic Review and Dose-Response Meta-Analysis of Nonexperimental Cohort Studies. Hypertension (Dallas, Tex. : 1979). 2024
- 8Alcohol consumption in relation to cognitive dysfunction and dementia: A systematic review and dose-response meta-analysis of comparative longitudinal studiesPMIDZarezadeh M, Mahmoudinezhad M, Faghfouri AH et al. · Ageing research reviews · 2024
Zarezadeh M, Mahmoudinezhad M, Faghfouri AH et al.. Alcohol consumption in relation to cognitive dysfunction and dementia: A systematic review and dose-response meta-analysis of comparative longitudinal studies. Ageing research reviews. 2024
- 9Dexmedetomidine as Adjunctive Therapy for the Treatment of Alcohol Withdrawal Syndrome: A Systematic Review and Meta-AnalysisPMIDFiore M, Alfieri A, Torretta G et al. · Pharmaceuticals (Basel, Switzerland) · 2024
Fiore M, Alfieri A, Torretta G et al.. Dexmedetomidine as Adjunctive Therapy for the Treatment of Alcohol Withdrawal Syndrome: A Systematic Review and Meta-Analysis. Pharmaceuticals (Basel, Switzerland). 2024
- 10Cancer risk based on alcohol consumption levels: a comprehensive systematic review and meta-analysis.PMIDJun S et al. · Epidemiol Health · 2023
Meta-analysis of prospective cohorts found a dose-response relationship between alcohol consumption and cancer risk, with elevated risks seen for several cancers even at lower intake levels.
- 11Phenobarbital and Alcohol Withdrawal Syndrome: A Systematic Review and Meta-AnalysisPMIDUmar Z, Haseeb Ul Rasool M, Muhammad S et al. · Cureus · 2023
Umar Z, Haseeb Ul Rasool M, Muhammad S et al.. Phenobarbital and Alcohol Withdrawal Syndrome: A Systematic Review and Meta-Analysis. Cureus. 2023
- 12Ketamine Treatment for Alcohol Use Disorder: A Systematic ReviewPMIDKelson M, Burnett JM, Matthews A et al. · Cureus · 2023
Kelson M, Burnett JM, Matthews A et al.. Ketamine Treatment for Alcohol Use Disorder: A Systematic Review. Cureus. 2023
- 13Alcohol-medication interactions: A systematic review and meta-analysis of placebo-controlled trialsPMIDTraccis F, Presciuttini R, Pani PP et al. · Neuroscience and biobehavioral reviews · 2022
Traccis F, Presciuttini R, Pani PP et al.. Alcohol-medication interactions: A systematic review and meta-analysis of placebo-controlled trials. Neuroscience and biobehavioral reviews. 2022
Reviews & position papers
2- 14Advances in the science and treatment of alcohol use disorder.PMIDWitkiewitz K et al. · Sci Adv · 2019
Review describes alcohol as a major contributor to preventable morbidity and mortality and summarizes the biologic and clinical drivers of alcohol use disorder.
- 15Alcohol consumption as a cause of cancer.PMIDConnor J · Addiction · 2017
Review concludes there is strong evidence that alcohol causes cancers of the oropharynx, larynx, esophagus, liver, colon, rectum, and breast.
Common questions.
Quick answers about Alcohol, drawn from the data on this page.
What is Alcohol?
Alcohol is not supported by NutriStack. Safety information only.
What are the side effects of Alcohol?
Reported side effects include impaired judgment and coordination, sedation, nausea and vomiting, sleep disruption, tolerance and withdrawal with repeated use, liver injury. This is educational information; check with a healthcare professional before use.
How strong is the evidence for Alcohol?
NutriStack rates this as Insufficient, meaning the body of evidence reviewed in NutriStack's tiering framework. Full tier criteria are at https://nutristackapp.com/methodology/evidence-tiers.
Use this with your stack
Alcohol in NutriStack.
Add it to your stack, see how it interacts with everything else you take, and get a Stack Score that updates the moment it does.