Bifidobacterium infantis 35624
Probiotic ·Exploratory record · not publication-reviewed ·Updated July 13, 2026
Bifidobacterium infantis 35624 is a probiotic strain best known for IBS symptom trials, especially abdominal pain, bloating, gas, and bowel dysfunction. Taxonomy has shifted toward Bifidobacterium longum subsp. infantis, but product labels often still use B. infantis 35624. Evidence is strain-specific and should not be generalized to all Bifidobacterium products.
Exploratory record, not a reviewed medical publication.
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This generated database record has not completed a claim-level review by a qualified human medical reviewer. Bibliography links and evidence labels are not approval. The page remains available for reference and is excluded from search indexing.
What the research says.
A quick, data-only summary. The full evidence, dosing, and sources are below.
Bifidobacterium infantis 35624 is a probiotic most often used for may reduce ibs abdominal pain and discomfort, may reduce bloating, gas, and incomplete evacuation, may improve global ibs symptom scores. NutriStack rates the overall evidence as moderate. A typical adult dose is Often 1 billion CFU daily in commercial products; trials have tested 1 million to 10 billion CFU with dose-specific effects, commonly taken as strain-verified b. infantis 35624 capsule with cfu guaranteed through expiration. This profile indexes 3 sources.
- Temporary gas, bloating, or stool changes
- Mild abdominal discomfort during initiation
- Rare infection risk in severely immunocompromised or critically ill people
- Severe immunocompromise, neutropenia, central venous catheter, or critical illness without clinician guidance
- Short bowel syndrome or D-lactic acidosis history without specialist input1,2
The bottom line
Evidence rating moderate. Most-documented uses: may reduce ibs abdominal pain and discomfort, may reduce bloating, gas, and incomplete evacuation, may improve global ibs symptom scores. 3 sources indexed (2005–2017), with 0 interaction records on file.
How it works, mechanistically.
Core mechanism
B. infantis 35624 appears to modulate gut immune signaling, barrier function, cytokine balance, and visceral sensitivity. IBS trials suggest benefit may involve reduced mucosal immune activation and improved symptom signaling rather than permanent colonization. Effects are generally transient and depend on host microbiome, product viability, and baseline symptoms.3,1
Dosing & protocol.
Probiotics act locally in the gut rather than being absorbed like nutrients. Taking with food may improve survival through gastric acid; avoid hot liquids.1,2
What it actually costs.
Real-world pricing across three quality tiers. Assumes B. infantis 35624 capsule.
Branded strain products cost more than generic probiotic blends but better match clinical evidence. Updated 2026-06-04.
Full safety detail.
Side effects
- Temporary gas, bloating, or stool changes
- Mild abdominal discomfort during initiation
- Rare infection risk in severely immunocompromised or critically ill people
- Allergic reaction to product excipients
Contraindications
Sources, by evidence tier.
Numbered references. Citations throughout the page link here.
Meta-analyses & systematic reviews
1- 1Efficacy of Bifidobacterium infantis 35624 in patients with irritable bowel syndrome: a meta-analysisYuan F et al. · Current Medical Research and Opinion · 2017
Pooled analyses supported some symptom effects but highlighted limited trial numbers and dose/formulation issues.
Randomized controlled trials
2- 2Efficacy of an encapsulated probiotic Bifidobacterium infantis 35624 in women with irritable bowel syndromeWhorwell PJ et al. · American Journal of Gastroenterology · 2006
The 1 x 10^8 CFU dose improved abdominal pain, bloating, bowel dysfunction, and composite symptoms versus placebo.
- 3Lactobacillus and bifidobacterium in irritable bowel syndrome: symptom responses and relationship to cytokine profilesO'Mahony L et al. · Gastroenterology · 2005
B. infantis improved several IBS symptoms and was associated with immune-marker changes.
Common questions.
Quick answers about Bifidobacterium infantis 35624, drawn from the data on this page.
What is Bifidobacterium infantis 35624?
Bifidobacterium infantis 35624 is a probiotic strain best known for IBS symptom trials, especially abdominal pain, bloating, gas, and bowel dysfunction. Taxonomy has shifted toward Bifidobacterium longum subsp. infantis, but product labels often still use B. infantis 35624. Evidence is strain-specific and should not be generalized to all Bifidobacterium products.
What is Bifidobacterium infantis 35624 used for?
Commonly cited benefits of Bifidobacterium infantis 35624 include: May reduce IBS abdominal pain and discomfort; May reduce bloating, gas, and incomplete evacuation; May improve global IBS symptom scores; May support mucosal immune balance. NutriStack rates the overall evidence as moderate.
What is a typical dose of Bifidobacterium infantis 35624?
A typical adult dose of Bifidobacterium infantis 35624 is Often 1 billion CFU daily in commercial products; trials have tested 1 million to 10 billion CFU with dose-specific effects. The commonly recommended form is Strain-verified B. infantis 35624 capsule with CFU guaranteed through expiration. These are general ranges, not personalized advice; confirm the right dose with a clinician.
What are the side effects of Bifidobacterium infantis 35624?
Reported side effects include temporary gas, bloating, or stool changes, mild abdominal discomfort during initiation, rare infection risk in severely immunocompromised or critically ill people, allergic reaction to product excipients. This is educational information; check with a healthcare professional before use.
How strong is the evidence for Bifidobacterium infantis 35624?
NutriStack rates this as Moderate, meaning several aligned RCTs or one large RCT plus supporting reviews. Full tier criteria are at https://nutristackapp.com/methodology/evidence-tiers.
Use this with your stack
Bifidobacterium infantis 35624 in NutriStack.
Add it to your stack, see how it interacts with everything else you take, and get a Stack Score that updates the moment it does.