Ginger Extract
Herb ·Exploratory record · not publication-reviewed ·Updated July 13, 2026
Warming root studied for nausea, digestion, and inflammatory-marker contexts.
Exploratory record, not a reviewed medical publication.
See the editorial and medical-review policies for the publication gate.
This generated database record has not completed a claim-level review by a qualified human medical reviewer. Bibliography links and evidence labels are not approval. The page remains available for reference and is excluded from search indexing.
What the research says.
A quick, data-only summary. The full evidence, dosing, and sources are below.
Ginger Extract is a herb most often used for nausea support, digestion, inflammatory-marker research. NutriStack rates the overall evidence as strong. A typical adult dose is 250-1,000 mg daily, commonly taken as standardized extract (5% gingerols). This profile indexes 20 sources.
The bottom line
Evidence rating strong. Most-documented uses: nausea support, digestion, inflammatory-marker research. 20 sources indexed (2000–2025), with 0 interaction records on file.
How it works, mechanistically.
Core mechanism
Gingerols and shogaols act on 5-HT3 serotonin receptors in the GI tract (antiemetic), inhibit COX-2 and LOX inflammatory enzymes, and enhance gastric motility.18
Dosing & protocol.
What it actually costs.
Real-world pricing across three quality tiers. Assumes Standardized Ginger Extract.
Assumes 250-1,000 mg/day. Vendor basis: NOW/iHerb, Vitacost, Life Extension, and Amazon marketplace; high-gingerol extracts cost more. Updated 2026-05-28.
The same dose, as food.
How much you'd eat to match a supplemental dose.
Extracts concentrate gingerols and shogaols more predictably than foods.
Full safety detail.
Sources, by evidence tier.
Numbered references. Citations throughout the page link here.
Meta-analyses & systematic reviews
13- 1Effectiveness of ginger supplementation in alleviating hyperemesis gravidarum: a systematic review and meta-analysisPMIDGao P, Chen B, Wang L · American journal of translational research · 2025
Gao P, Chen B, Wang L. Effectiveness of ginger supplementation in alleviating hyperemesis gravidarum: a systematic review and meta-analysis. American journal of translational research. 2025
- 2Systematic review of the impact of ginger extract and alpinetin on pregnancy outcomes in animal modelsPMIDWilliams JT, Tiani KA, Foster MJ et al. · BMC complementary medicine and therapies · 2025
Williams JT, Tiani KA, Foster MJ et al.. Systematic review of the impact of ginger extract and alpinetin on pregnancy outcomes in animal models. BMC complementary medicine and therapies. 2025
- 3Pharmacological properties of ginger (Zingiber officinale): what do meta-analyses say? a systematic reviewPMIDPaudel KR, Orent J, Penela OG · Frontiers in pharmacology · 2025
Paudel KR, Orent J, Penela OG. Pharmacological properties of ginger (Zingiber officinale): what do meta-analyses say? a systematic review. Frontiers in pharmacology. 2025
- 4Ginger for Pain Management in Primary Dysmenorrhea: A Systematic Review and Meta-AnalysisPMIDMoshfeghinia R, Salmanpour N, Ghoshouni H et al. · Journal of Integrative and Complementary Medicine · 2024
Meta-analysis reported reduced dysmenorrhea pain measures in some comparisons; do not position ginger as an NSAID-equivalent treatment.
- 5Effectivity of oral ginger supplementation for chemotherapy induced nausea and vomiting (CINV) in children: A systematic review of clinical trialsPMIDHardi H, Estuworo GK, Louisa M · Journal of Ayurveda and integrative medicine · 2024
Hardi H, Estuworo GK, Louisa M. Effectivity of oral ginger supplementation for chemotherapy induced nausea and vomiting (CINV) in children: A systematic review of clinical trials. Journal of Ayurveda and integrative medicine. 2024
- 6Ginger supplementation for the treatment of non-alcoholic fatty liver disease: a meta-analysis of randomized controlled trialsPMIDZhou Q, Peng Y, Chen F et al. · African health sciences · 2023
Zhou Q, Peng Y, Chen F et al.. Ginger supplementation for the treatment of non-alcoholic fatty liver disease: a meta-analysis of randomized controlled trials. African health sciences. 2023
- 7Effect of ginger in the treatment of nausea and vomiting compared with vitamin B6 and placebo during pregnancy: a meta-analysisPMIDHu Y, Amoah AN, Zhang H et al. · The Journal of Maternal-Fetal & Neonatal Medicine · 2022
Ginger was significantly more effective than placebo and similarly effective to vitamin B6 in reducing nausea and vomiting during pregnancy, with a good safety profile.
- 8Effect of ginger (Zingiber officinale) on inflammatory markers: A systematic review and meta-analysis of randomized controlled trialsPMIDJalali M et al. · Phytother Res · 2020
Meta-analysis of 16 RCTs (1,010 participants) demonstrated significant reduction in CRP, hs-CRP, and TNF-alpha levels with ginger supplementation
- 9Does the Oral Administration of Ginger Reduce Chemotherapy-Induced Nausea and Vomiting?: A Meta-analysis of 10 Randomized Controlled TrialsPMIDSaneei Totmaj A et al. · Phytother Res · 2019
Ginger displayed significant efficacy in controlling chemotherapy-induced nausea and vomiting with an odds ratio of 0.71
- 10Does ginger supplementation lower blood pressure? A systematic review and meta-analysis of clinical trialsPMIDHasani H, Arab A, Hadi A, Pourmasoumi M, Ghavami A, Miraghajani M · Phytotherapy Research · 2019
Ginger supplementation significantly reduced both systolic and diastolic blood pressure in a meta-analysis of clinical trials, with effects potentially mediated by ACE inhibition and vasodilation.
- 11Efficacy and safety of ginger in osteoarthritis patients: a meta-analysis of randomized placebo-controlled trialsPMIDBartels EM et al. · Osteoarthritis Cartilage · 2015
Ginger showed moderate efficacy for osteoarthritis pain relief with an acceptable safety profile
- 12A systematic review and meta-analysis of the effect and safety of ginger in the treatment of pregnancy-associated nausea and vomitingSource linkedPMIDViljoen E, Visser J, Koen N, Musekiwa A · Nutr J · 2014
- 13Efficacy of ginger for nausea and vomiting: a systematic review of randomized clinical trialsSource linkedPMIDErnst E, Pittler MH · Br J Anaesth · 2000
Reviews & position papers
4- 14Orally consumed ginger and human health: an umbrella reviewPMIDAnh NH et al. · Crit Rev Food Sci Nutr · 2022
Dietary consumption of ginger appears safe and may exert beneficial effects on human health and well-being across multiple conditions
- 15Ginger on Human Health: A Comprehensive Systematic Review of 109 Randomized Controlled TrialsPMIDAnh NH et al. · Nutrients · 2020
Systematic review of 109 RCTs showing promising efficacy of ginger for nausea/vomiting, metabolic syndrome, and pain management
- 16Ginger in gastrointestinal disorders: A systematic review of clinical trialsPMIDNikkhah Bodagh M et al. · Food Sci Nutr · 2019
Systematic review showed ginger enhances gastric motility and has anti-nausea properties for various gastrointestinal conditions
- 17Anti-oxidative and anti-inflammatory effects of ginger in health and physical activity: review of current evidenceSource linkedPMIDMashhadi NS, Ghiasvand R, Askari G et al. · Int J Prev Med · 2013
Mechanistic & preclinical
1- 18[6]-Gingerol inhibits COX-2 expression by blocking the activation of p38 MAP kinase and NF-kappaB in phorbol ester-stimulated mouse skinPMIDKim SO et al. · Oncogene · 2005
[6]-Gingerol inhibits TPA-induced COX-2 expression by blocking the p38 MAP kinase-NF-kappaB signaling pathway
Reference material
2Common questions.
Quick answers about Ginger Extract, drawn from the data on this page.
What is Ginger Extract?
Warming root studied for nausea, digestion, and inflammatory-marker contexts.
What is Ginger Extract used for?
Commonly cited benefits of Ginger Extract include: Nausea support; Digestion; Inflammatory-marker research. NutriStack rates the overall evidence as strong.
What is a typical dose of Ginger Extract?
A typical adult dose of Ginger Extract is 250-1,000 mg daily. The commonly recommended form is Standardized extract (5% gingerols). These are general ranges, not personalized advice; confirm the right dose with a clinician.
What are the side effects of Ginger Extract?
Reported side effects include heartburn, mild blood thinning, mouth irritation. This is educational information; check with a healthcare professional before use.
How strong is the evidence for Ginger Extract?
NutriStack rates this as Strong, meaning multiple high-quality meta-analyses or systematic reviews converge on the same finding. Full tier criteria are at https://nutristackapp.com/methodology/evidence-tiers.
Use this with your stack
Ginger Extract in NutriStack.
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