NSTK · 01.2026Independent supplement reference
NutriStack
Edition 1.0Updated July 13, 2026

Resveratrol

Herb ·Exploratory record · not publication-reviewed ·Updated July 13, 2026

Polyphenol from red wine and grapes studied for metabolic, vascular, and oxidative-stress markers. Best taken with a fat source for absorption.

Evidence tier
Emerging
Indexed sources
20 2014–2025
Interactions
0
Cost / month
$7.50 budget
Read the sources → Compare profiles
Publication status

Exploratory record, not a reviewed medical publication.

See the editorial and medical-review policies for the publication gate.

This generated database record has not completed a claim-level review by a qualified human medical reviewer. Bibliography links and evidence labels are not approval. The page remains available for reference and is excluded from search indexing.

In short

What the research says.

A quick, data-only summary. The full evidence, dosing, and sources are below.

Resveratrol is a herb most often used for healthy-aging research, cardiometabolic markers, oxidative-stress support. NutriStack rates the overall evidence as emerging. A typical adult dose is 150–500 mg trans-resveratrol daily, commonly taken as trans-resveratrol (the bioactive isomer); micronized for better absorption. This profile indexes 20 sources.

What it's good for
  • Healthy-aging research15,5
  • Cardiometabolic markers3,7
  • Oxidative-stress support20
  • Blood sugar support9,10
What to watch for
  • GI upset at high doses
  • Blood thinning
  • Estrogenic effects at high doses
  • Blood thinners9,10
  • Hormone-sensitive cancers

The bottom line

Evidence rating emerging. Most-documented uses: healthy-aging research, cardiometabolic markers, oxidative-stress support. 20 sources indexed (2014–2025), with 0 interaction records on file.

The science

How it works, mechanistically.

Core mechanism

Influences SIRT1, AMPK, Nrf2, NF-kB, and mitochondrial pathways in preclinical or mechanistic research; human clinical outcome evidence is mixed and should not be framed as proven longevity benefit.15

Class
Polyphenol
Found in food
Red grapes, Red wine, Peanuts
Low-status signs
Not applicable
Absorption
Fat-soluble; take with food
Dosing

Dosing & protocol.

Common range
150–500 mg trans-resveratrol daily
Recommended form
Trans-resveratrol (the bioactive isomer); micronized for better absorption

Take with fat-containing meal; highly bioavailable but rapidly metabolized3,5

Cost

What it actually costs.

Real-world pricing across three quality tiers. Assumes Trans-Resveratrol.

BudgetBest value
$7.50 /mo
$0.25 per dose
Mid
$16.50 /mo
$0.55 per dose
Premium
$33.00 /mo
$1.10 per dose

Assumes 150-300 mg/day from goal dosage. Vendor basis: NOW/iHerb, Vitacost, Life Extension, and Amazon marketplace; micronized or high-purity trans-resveratrol costs more. Updated 2026-05-28.

From food

The same dose, as food.

How much you'd eat to match a supplemental dose.

150 mg trans-resveratrol
Not practical from food alone; red grapes and berries provide far smaller amounts

Supplemental longevity-style doses are much higher than dietary intake.

5-10 mg resveratrol
A generous serving of red grapes, blueberries, and peanuts

Food provides small amounts, not supplement-scale amounts.

Safety

Full safety detail.

Side effects

  • GI upset at high doses
  • Blood thinning
  • Estrogenic effects at high doses

Contraindications

  • Blood thinners9,10
  • Hormone-sensitive cancers
  • Upcoming surgery
Sources

Sources, by evidence tier.

Numbered references. Citations throughout the page link here.

Meta-analyses & systematic reviews

14

Reviews & position papers

4

Reference material

2
FAQ

Common questions.

Quick answers about Resveratrol, drawn from the data on this page.

What is Resveratrol?

Polyphenol from red wine and grapes studied for metabolic, vascular, and oxidative-stress markers. Best taken with a fat source for absorption.

What is Resveratrol used for?

Commonly cited benefits of Resveratrol include: Healthy-aging research; Cardiometabolic markers; Oxidative-stress support; Blood sugar support. NutriStack rates the overall evidence as emerging.

What is a typical dose of Resveratrol?

A typical adult dose of Resveratrol is 150–500 mg trans-resveratrol daily. The commonly recommended form is Trans-resveratrol (the bioactive isomer); micronized for better absorption. These are general ranges, not personalized advice; confirm the right dose with a clinician.

What are the side effects of Resveratrol?

Reported side effects include gi upset at high doses, blood thinning, estrogenic effects at high doses. This is educational information; check with a healthcare professional before use.

How strong is the evidence for Resveratrol?

NutriStack rates this as Emerging, meaning early RCT signal, mechanistic data, or limited human evidence. Full tier criteria are at https://nutristackapp.com/methodology/evidence-tiers.

Use this with your stack

Resveratrol in NutriStack.

Add it to your stack, see how it interacts with everything else you take, and get a Stack Score that updates the moment it does.

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NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.