Vitamin B7
Vitamin ·Exploratory record · not publication-reviewed ·Updated July 13, 2026
Known as the 'beauty vitamin' for its role in hair, skin, and nail health. Also essential for macronutrient metabolism.
Exploratory record, not a reviewed medical publication.
See the editorial and medical-review policies for the publication gate.
This generated database record has not completed a claim-level review by a qualified human medical reviewer. Bibliography links and evidence labels are not approval. The page remains available for reference and is excluded from search indexing.
What the research says.
A quick, data-only summary. The full evidence, dosing, and sources are below.
Vitamin B7 is a vitamin most often used for hair health (only in biotin deficiency), nail strength, skin health. NutriStack rates the overall evidence as moderate. A typical adult dose is 2,500–10,000 mcg daily, commonly taken as d-biotin. This profile indexes 17 sources.
The bottom line
Evidence rating moderate. Most-documented uses: hair health (only in biotin deficiency), nail strength, skin health. 17 sources indexed (2017–2026), with 0 interaction records on file.
How it works, mechanistically.
Core mechanism
Serves as a prosthetic group for carboxylase enzymes: pyruvate carboxylase (gluconeogenesis), acetyl-CoA carboxylase (fatty acid synthesis), propionyl-CoA carboxylase (amino acid metabolism), and methylcrotonyl-CoA carboxylase (leucine catabolism).
Dosing & protocol.
At recommended doses (2,500-10,000 mcg), lab test interference is virtually guaranteed. FDA reported at least one death from falsely low troponin. Affected tests: troponin, thyroid panel, beta-hCG, PSA, vitamin D. Stop at least 72 hours before any blood work.1,11
What it actually costs.
Real-world pricing across three quality tiers. Assumes Biotin.
Assumes a standard daily beauty-support dose. Biotin is inexpensive, but users should still remember it can interfere with some lab assays. Updated 2026-04-02.
The same dose, as food.
How much you'd eat to match a supplemental dose.
High-dose biotin can interfere with lab tests; foods provide much smaller amounts.
Full safety detail.
Sources, by evidence tier.
Numbered references. Citations throughout the page link here.
Randomized controlled trials
2- 1Oral Supplementation with l-Cystine, Serenoa repens, Cucurbita pepo, and Pygeum africanum in Chronic Telogen Effluvium and Androgenetic Alopecia: A Double-Blind, Placebo-Controlled, Randomized Clinical StudyPMIDPiquero-Casals J, Saceda-Corralo D, Aladren S et al. · Skin Appendage Disorders · 2025
In 80 patients, hair density increased by 12.3 hairs/cm2 after 6 months with the oral supplement containing vitamins and micronutrients. The supplement was well tolerated with no moderate or severe adverse events.
- 2Efficacy of 5% topical minoxidil versus 5 mg oral biotin versus topical minoxidil and oral biotin on hair growth in men: randomized, crossover, clinical trialPMIDValentim FO, Miola AC, Miot HA et al. · Anais brasileiros de dermatologia · 2024
Valentim FO, Miola AC, Miot HA et al.. Efficacy of 5% topical minoxidil versus 5 mg oral biotin versus topical minoxidil and oral biotin on hair growth in men: randomized, crossover, clinical trial. Anais brasileiros de dermatologia. 2024
Reviews & position papers
13- 3BiotinPMIDBistas KG, Tadi P · 2026
Bistas KG, Tadi P. Biotin. 2026
- 4Biotin mitigates the development of manganese-induced, Parkinson's disease-related neurotoxicity in Drosophila and human neuronsPMIDLai Y, Reina-Gonzalez P, Maor G et al. · Science signaling · 2025
Lai Y, Reina-Gonzalez P, Maor G et al.. Biotin mitigates the development of manganese-induced, Parkinson's disease-related neurotoxicity in Drosophila and human neurons. Science signaling. 2025
- 5Biotin rescues manganese-induced Parkinson's disease phenotypes and neurotoxicityPMIDLai Y, Reina-Gonzalez P, Maor G et al. · bioRxiv : the preprint server for biology · 2023
Lai Y, Reina-Gonzalez P, Maor G et al.. Biotin rescues manganese-induced Parkinson's disease phenotypes and neurotoxicity. bioRxiv : the preprint server for biology. 2023
- 6Biotin induced biochemical hyperthyroidism: a case report and review of the literaturePMIDJames A, Stalan J, Kuzhively J · Journal of medical case reports · 2023
James A, Stalan J, Kuzhively J. Biotin induced biochemical hyperthyroidism: a case report and review of the literature. Journal of medical case reports. 2023
- 7Biotin interference with thyroid function tests: a systematic reviewSource linkedPMIDSamarasinghe S, Meah F, Singh V et al. · J Endocr Soc · 2020
- 8Susceptibility of Cardiac Troponin Assays to Biotin InterferencePMIDFrame IJ, Bhargava R · Clin Chem · 2019
Biotin interference is possible at plasma concentrations achievable by OTC supplements; may lead to delayed/missed diagnosis of myocardial injury with some troponin assays
- 9Best practices in mitigating the risk of biotin interference with laboratory testingPMIDBowen R et al. · Clin Biochem · 2019
Patients should abstain from biotin supplements for at least 48h before blood work; 92 cases of suspected biotin interference reported to FDA since 2016
- 10Rethinking biotin therapy for hair, nail, and skin disordersPMIDLipner SR · J Am Acad Dermatol · 2018
Despite enormous market hype, biotin's efficacy for hair growth remains largely unsubstantiated in scientific literature; benefits limited to those with biotin deficiency
- 11Biotin for the treatment of nail disease: what is the evidence?PMIDLipner SR, Scher RK · J Dermatolog Treat · 2018
63% of patients (22/35) showed clinical improvement in brittle nails with biotin supplementation in a small retrospective study
- 12Comprehensive assessment of biotin interference in immunoassaysPMIDTrambas CM et al. · Clin Chem · 2018
Biotin falsely increases analyte concentration in competitive immunoassays (positive interference) and shows negative interference in sandwich immunoassays
- 13Biotin conjugated organic molecules and proteins for cancer therapy: A reviewPMIDMaiti S, Paira P · European journal of medicinal chemistry · 2018
Maiti S, Paira P. Biotin conjugated organic molecules and proteins for cancer therapy: A review. European journal of medicinal chemistry. 2018
- 14A Review of the Use of Biotin for Hair LossPMIDPatel DP et al. · Skin Appendage Disord · 2017
All 18 reported cases showed clinical improvement with biotin, but all had underlying pathology; no RCTs exist for biotin and hair loss in healthy individuals
- 15Biotin interference with routine clinical immunoassays: understand the causes and mitigate the risksSource linkedPMIDLi D, Radulescu A, Shrestha RT et al. · Biotin interference in clinical immunoassays · 2017
Reference material
2- 16Reininghaus EZ, Platzer M, Kohlhammer-Dohr A et al.. PROVIT: Supplementary Probiotic Treatment and Vitamin B7 in Depression-A Randomized Controlled Trial. Nutrients. 2020Source linkedPMID
- 17Evidence Review: Natural Hair Supplements: Biotin and Collagen. Plastic and aesthetic nursing. 2023Source linkedPMID
Common questions.
Quick answers about Vitamin B7, drawn from the data on this page.
What is Vitamin B7?
Known as the 'beauty vitamin' for its role in hair, skin, and nail health. Also essential for macronutrient metabolism.
What is Vitamin B7 used for?
Commonly cited benefits of Vitamin B7 include: Hair health (only in biotin deficiency); Nail strength; Skin health; Blood sugar support; Energy metabolism. NutriStack rates the overall evidence as moderate.
What is a typical dose of Vitamin B7?
A typical adult dose of Vitamin B7 is 2,500–10,000 mcg daily. The commonly recommended form is D-biotin. These are general ranges, not personalized advice; confirm the right dose with a clinician.
What are the side effects of Vitamin B7?
Reported side effects include may interfere with lab tests, generally very safe. This is educational information; check with a healthcare professional before use.
How strong is the evidence for Vitamin B7?
NutriStack rates this as Moderate, meaning several aligned RCTs or one large RCT plus supporting reviews. Full tier criteria are at https://nutristackapp.com/methodology/evidence-tiers.
Use this with your stack
Vitamin B7 in NutriStack.
Add it to your stack, see how it interacts with everything else you take, and get a Stack Score that updates the moment it does.