From the databaseWhat the row says.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
Scope
Supplement × Supplement
Last verified
June 4, 2026
SynergyEmerging evidence
What is happening. Both are used for insulin sensitivity and may have additive glucose-lowering effects.
Mechanism. Inositol second-messenger effects plus alpha-lipoic-acid insulin-sensitizing activity.
Recommendation. Start one product at a time and monitor dizziness, sweating, shakiness, or glucose readings when relevant.
Stack Score
How it moves the number.
Effect on the composite score
If both Alpha-Lipoic Acid and Myo-Inositol & D-Chiro-Inositol are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
SourcesSources, by evidence tier.
Every claim on this page is cited. PMIDs link straight to PubMed.
Reference material
1- 1Bevilacqua A et al. Inositol consensus review. Eur J Obstet Gynecol Reprod Biol. 2015.Needs sourceNo link