NutriStack
Alpha-Lipoic Acid and Vitamin B7, a conflict.
Alpha-lipoic acid competes with biotin (B7) for the SMVT transporter in the gut, potentially reducing biotin absorption.
One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.
From the interaction database
What the row says.
Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.
At a glance
- Substances
- Alpha-Lipoic Acid and Vitamin B7
- Pair type
- Conflict
- Evidence (highest tier)
- Moderate
- Source citations
- 1 source
- Stack Score effect
- −10 to your Stack Score (per scored conflict row).
- Scope
- Supplement × Supplement
- Last verified
- May 30, 2026
Conflict · Moderate evidence
Conflict
What is happening. Alpha-lipoic acid competes with biotin (B7) for the SMVT transporter in the gut, potentially reducing biotin absorption.
Mechanism. Both biotin and lipoic acid are transported by the sodium-dependent multivitamin transporter (SMVT/SLC5A6) in the intestine. ALA competitively inhibits biotin uptake.
Recommendation. Separate ALA and biotin by at least 2 hours. If taking ALA long-term, consider extra biotin supplementation.
Minimum separation. 120
Stack Score
How this pair moves the number.
Effect on the composite score
If both Alpha-Lipoic Acid and Vitamin B7 are in the same stack, this pair applies −10 to your Stack Score (per scored conflict row).
The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.
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