NutriStack
Amiodarone and Coenzyme Q10 Ubiquinol, a synergy.
Amiodarone has mitochondrial effects, and CoQ10 is involved in mitochondrial electron transport. Direct evidence that CoQ10 changes amiodarone outcomes is limited.
One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.
From the interaction database
What the row says.
Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.
At a glance
- Substances
- Amiodarone and Coenzyme Q10 Ubiquinol
- Pair type
- Synergy
- Evidence (highest tier)
- Emerging
- Source citations
- 1 source
- Stack Score effect
- +2 to your Stack Score (per scored synergy row).
- Scope
- Supplement × Prescription
- Last verified
- May 30, 2026
Synergy · Emerging evidence
Synergy
What is happening. Amiodarone has mitochondrial effects, and CoQ10 is involved in mitochondrial electron transport. Direct evidence that CoQ10 changes amiodarone outcomes is limited.
Mechanism. Amiodarone can affect mitochondrial enzymes, while CoQ10 participates in mitochondrial electron transport. Clinical relevance of supplementation during amiodarone therapy remains uncertain.
Recommendation. Discuss CoQ10 with the prescriber managing amiodarone, especially if heart-failure, arrhythmia, or anticoagulant issues are present; do not assume it changes amiodarone safety or effectiveness.
Stack Score
How this pair moves the number.
Effect on the composite score
If both Amiodarone and Coenzyme Q10 Ubiquinol are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.
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