NutriStack
Apigenin and Magnesium Glycinate, a synergy.
Both promote relaxation and sleep through GABAergic and glutamate-modulating pathways.
One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.
From the interaction database
What the row says.
Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.
At a glance
- Substances
- Apigenin and Magnesium Glycinate
- Pair type
- Synergy
- Evidence (highest tier)
- Emerging
- Source citations
- 1 source
- Stack Score effect
- +2 to your Stack Score (per scored synergy row).
- Scope
- Supplement × Supplement
- Last verified
- May 30, 2026
Synergy · Emerging evidence
Synergy
What is happening. Both promote relaxation and sleep through GABAergic and glutamate-modulating pathways.
Mechanism. Apigenin positively modulates GABA-A receptors. Magnesium blocks excitatory NMDA glutamate receptors. Glycine from magnesium glycinate adds inhibitory neurotransmission.
Recommendation. Combine for a gentle, non-habit-forming sleep support stack.
Sources (1)
- Salehi B et al. The therapeutic potential of apigenin. Int J Mol Sci. 2019
Stack Score
How this pair moves the number.
Effect on the composite score
If both Apigenin and Magnesium Glycinate are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.
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