From the databaseWhat the row says.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
Scope
Supplement × Supplement
Last verified
June 4, 2026
SynergyEmerging evidence
What is happening. Both are used for immune resilience and may be complementary.
Mechanism. Innate immune priming plus antioxidant and leukocyte support.
Recommendation. Use moderate doses; avoid very high vitamin C doses if kidney stone risk is high.
Stack Score
How it moves the number.
Effect on the composite score
If both Beta-Glucan and Vitamin C are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
SourcesSources, by evidence tier.
Every claim on this page is cited. PMIDs link straight to PubMed.
Reference material
1- 1Dharsono T et al. Yeast beta-glucan URTI trial. J Am Coll Nutr. 2018.Needs sourceNo link