From the databaseWhat the row says.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
Scope
Supplement × Supplement
Last verified
June 4, 2026
SynergyInsufficient evidence
What is happening. Zinc and probiotics may both support mucosal immune function, though direct BB536-zinc trial data are limited.
Mechanism. Complementary immune and epithelial-barrier support mechanisms.
Recommendation. Reasonable to combine at standard zinc doses; avoid chronic high-dose zinc unless monitored.
Stack Score
How it moves the number.
Effect on the composite score
If both Bifidobacterium longum BB536 and Zinc are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
SourcesSources, by evidence tier.
Every claim on this page is cited. PMIDs link straight to PubMed.
Reference material
1- 1Matsumoto M et al. BB536 defecation study. World Journal of Gastroenterology. 2013.Needs sourceNo link