Boron and Tribulus Terrestris, a synergy.
Boron can raise free testosterone by lowering sex hormone binding globulin and reducing conversion of testosterone to estradiol, a mechanism that complements Tribulus rather than overlapping with it.
One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
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At a glance
- Substances
- Boron and Tribulus Terrestris
- Pair type
- Synergy
- Evidence (highest tier)
- Emerging
- Source citations
- 2 sources
- Stack Score effect
- +2 to your Stack Score (per scored synergy row).
- Scope
- Supplement × Supplement
- Last verified
- May 30, 2026
Synergy · Emerging evidence
Synergy
What is happening. Boron can raise free testosterone by lowering sex hormone binding globulin and reducing conversion of testosterone to estradiol, a mechanism that complements Tribulus rather than overlapping with it.
Mechanism. Boron has been reported in small studies to reduce SHBG, freeing more bioavailable testosterone, and to lower estradiol, while Tribulus is proposed to act on androgen and nitric oxide pathways, so the two influence androgen availability through distinct steps.
Recommendation. Boron 3 to 6mg daily can be paired with Tribulus for free testosterone support. Stay within the boron tolerable upper intake level of 20mg daily and do not megadose.
Sources (2)
- Naghii MR, Mofid M, Asgari AR, Hedayati M, Daneshpour MS. Comparative effects of daily and weekly boron supplementation on plasma steroid hormones and proinflammatory cytokines. Journal of Trace Elements in Medicine and Biology. 2011.
- Neychev V, Mitev V. Pro-sexual and androgen enhancing effects of Tribulus terrestris L.: Fact or Fiction. Journal of Ethnopharmacology. 2016.
Stack Score
How this pair moves the number.
Effect on the composite score
If both Boron and Tribulus Terrestris are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.
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