Boron and Calcium, a synergy.
Boron reduces urinary calcium excretion and supports calcium utilization for bone health.
One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.
From the interaction database
What the row says.
Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.
At a glance
- Pair type
- Synergy
- Evidence (highest tier)
- Moderate
- Source citations
- 4 sources
- Stack Score effect
- +2 to your Stack Score (per scored synergy row).
- Scope
- Supplement × Supplement
- Last verified
- May 30, 2026
Synergy · Moderate evidence
Synergy
What is happening. Boron reduces urinary calcium excretion and supports calcium utilization for bone health.
Mechanism. Boron reduces urinary excretion of calcium and magnesium, likely by influencing renal tubular reabsorption and steroid hormone metabolism.
Recommendation. 3mg boron daily may help retain calcium and support bone mineral density.
Sources (4)
- Nielsen FH et al. Effect of dietary boron on mineral, estrogen, and testosterone metabolism in postmenopausal women. FASEB J. 1987
- Rondanelli M, Faliva MA, Barrile GC et al.. Nutrition, Physical Activity, and Dietary Supplementation to Prevent Bone Mineral Density Loss: A Food Pyramid. Nutrients. 2021. PMID 35010952
- Liu C, Kuang X, Li K, Guo X, Deng Q, Li D. Effects of combined calcium and vitamin D supplementation on osteoporosis in postmenopausal women: a systematic review and meta-analysis of randomized controlled trials. Food & Function. 2020. PMID 33237064
- Yao P, Bennett D, Mafham M et al.. Vitamin D and Calcium for the Prevention of Fracture: A Systematic Review and Meta-analysis. JAMA Network Open. 2019. PMID 31860103
Stack Score
How this pair moves the number.
Effect on the composite score
If both Boron and Calcium are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.
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