From the databaseWhat the row says.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
Scope
Supplement × Prescription
Last verified
June 4, 2026
CautionStrong evidence
What is happening. Calcium supplements can combine with calcitriol to cause hypercalcemia, hypercalciuria, kidney stones, or soft tissue calcification.
Mechanism. Calcitriol increases intestinal calcium absorption while supplements increase calcium load.
Recommendation. Use only the calcium amount prescribed and monitor serum calcium as directed.
Stack Score
How it moves the number.
Effect on the composite score
If both Calcitriol and Calcium are in the same stack, this pair applies −5 to your Stack Score (per scored caution row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
SourcesSources, by evidence tier.
Every claim on this page is cited. PMIDs link straight to PubMed.
Reference material
1- 1U.S. National Library of Medicine. Calcitriol Capsules and Oral Solution US Prescribing Information. 2026.Needs sourceNo link