Supplement × Prescription·timing-sensitive·Strong evidence
Calcium taken near oral ibandronate can markedly reduce absorption and treatment efficacy.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
What is happening. Calcium taken near oral ibandronate can markedly reduce absorption and treatment efficacy.
Mechanism. Divalent cations chelate bisphosphonates and prevent absorption.
Recommendation. Take calcium later in the day, at least 60 minutes after ibandronate and preferably with a meal.
Space the doses apart by at least this window to avoid the conflict.
Effect on the composite score
If both Calcium and Ibandronate are in the same stack, this pair applies −5 to your Stack Score (per scored timing-sensitive row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
Every claim on this page is cited. PMIDs link straight to PubMed.
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NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.
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