NutriStack
Boron and Vitamin D3, a synergy.
Boron supports vitamin D metabolism and may increase the half-life of 25(OH)D in the body.
One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.
From the interaction database
What the row says.
Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.
At a glance
- Substances
- Boron and Vitamin D3
- Pair type
- Synergy
- Evidence (highest tier)
- Emerging
- Source citations
- 2 sources
- Stack Score effect
- +2 to your Stack Score (per scored synergy row).
- Scope
- Supplement × Supplement
- Last verified
- May 30, 2026
Synergy · Emerging evidence
Synergy
What is happening. Boron supports vitamin D metabolism and may increase the half-life of 25(OH)D in the body.
Mechanism. Boron appears to inhibit 24-hydroxylase (CYP24A1), the enzyme that catabolizes 25(OH)D and 1,25(OH)2D, thereby extending vitamin D half-life.
Recommendation. 3-6mg boron may enhance vitamin D status, particularly when D levels are suboptimal.
Sources (2)
- Pizzorno L. Nothing boring about boron. Integr Med (Encinitas). 2015
- Chang MC, Choo YJ. Effects of Whey Protein, Leucine, and Vitamin D Supplementation in Patients with Sarcopenia: A Systematic Review and Meta-Analysis.. Nutrients. 2023. PMID 36771225
Stack Score
How this pair moves the number.
Effect on the composite score
If both Boron and Vitamin D3 are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.
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