NutriStack
Boswellia and Cat's Claw, a synergy.
Pairing provides complementary anti-inflammatory action, with Boswellia inhibiting 5-lipoxygenase and Cat's Claw suppressing NF-kB signaling.
One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.
From the interaction database
What the row says.
Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.
At a glance
- Substances
- Boswellia and Cat's Claw
- Pair type
- Synergy
- Evidence (highest tier)
- Emerging
- Source citations
- 2 sources
- Stack Score effect
- +2 to your Stack Score (per scored synergy row).
- Scope
- Supplement × Supplement
- Last verified
- May 30, 2026
Synergy · Emerging evidence
Synergy
What is happening. Pairing provides complementary anti-inflammatory action, with Boswellia inhibiting 5-lipoxygenase and Cat's Claw suppressing NF-kB signaling.
Mechanism. Boswellic acids inhibit 5-lipoxygenase and leukotriene synthesis while Cat's Claw alkaloids inhibit NF-kB and TNF-alpha, hitting distinct arms of the inflammatory cascade.
Recommendation. Reasonable to combine for joint and inflammatory support. No timing constraint needed; take with food to improve tolerability.
Sources (2)
- Ammon HPT, Boswellic acids in chronic inflammatory diseases, Planta Medica, 2006
- Sandoval M et al., Anti-inflammatory and antioxidant activities of cat's claw, Phytomedicine, 2002
Stack Score
How this pair moves the number.
Effect on the composite score
If both Boswellia and Cat's Claw are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.
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