Cat's Claw and Fish Oil, a caution.
Both agents have mild antiplatelet activity, so combining them may modestly increase bleeding tendency, especially with anticoagulant or antiplatelet drugs.
One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.
From the interaction database
What the row says.
Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.
At a glance
- Substances
- Cat's Claw and Fish Oil
- Pair type
- Caution
- Evidence (highest tier)
- Emerging
- Source citations
- 2 sources
- Stack Score effect
- −5 to your Stack Score (per scored caution row).
- Scope
- Supplement × Supplement
- Last verified
- May 30, 2026
Caution · Emerging evidence
Caution
What is happening. Both agents have mild antiplatelet activity, so combining them may modestly increase bleeding tendency, especially with anticoagulant or antiplatelet drugs.
Mechanism. Cat's Claw may inhibit platelet aggregation and fish oil omega-3 fatty acids reduce thromboxane A2 generation and platelet aggregation, giving a potentially additive antiplatelet effect.
Recommendation. Generally fine for most people, but monitor for easy bruising or bleeding and stop both 1 to 2 weeks before surgery. Use caution if on blood thinners.
Sources (2)
- Heck AM, DeWitt BA, Lukes AL, Potential interactions between alternative therapies and warfarin, American Journal of Health-System Pharmacy, 2000. Potential interactions between alternative therapies and warfarin. Am J Health Syst Pharm. 2000. PMID 10902065
- Wachtel-Galor S, Benzie IFF (eds), Herbal Medicine: Biomolecular and Clinical Aspects, 2nd edition, 2011
Stack Score
How this pair moves the number.
Effect on the composite score
If both Cat's Claw and Fish Oil are in the same stack, this pair applies −5 to your Stack Score (per scored caution row).
The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.
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