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Supplement × Supplement·Evidence index

Boswellia and Curcumin Phytosome: what the research found

PubMed indexes 7 records that name Boswellia and Curcumin Phytosome together, either in the title or in an interaction, co-administration, or pharmacokinetic context. The key findings come first, in the authors’ own words, followed by every study with its design and PubMed link.

A summary of published research, not medical advice. A pharmacist can check any combination against your full list of medicines and supplements.

Key findings

What the studies concluded.

Reviews and human studies first. Each quote is the authors’ own conclusion about their study, not a NutriStack assessment, and a single study is not a consensus.

“The results of our study suggest that curcuminoid and boswellia formulations could be a valuable addition to the knee OA treatment regimens by relieving symptoms while reducing safety risks. The current body of evidence is not adequate in size or quality to make any meaningful clinical practice recommendations. Further research through large, high quality RCTs probably investigating the synergistic effect of…”

Bannuru et al. · 2018 · Review or meta-analysis · details

“These data suggest that interactions between the major constituents of this supplement combination are unlikely and therefore could be investigated to manage patients with osteoarthritis without significant concerns for possible pharmacokinetic interactions.”

Liu et al. · 2020 · Human study · details

“Our data suggest a positive effect of supplementation with curcumin and BSE on glycoxidation and lipid peroxidation in chronically exercising master athletes.”

The research

7 studies naming Boswellia and Curcumin Phytosome.

Strongest relevance first: papers naming both substances in the title, then human trials and systematic reviews.

Efficacy of curcumin and Boswellia for knee osteoarthritis: Systematic review and meta-analysis.

Seminars in arthritis and rheumatism · 2018 · PMID 29622343

Meta-AnalysisResearch Support, N.I.H., ExtramuralSystematic ReviewHuman subjects

“The results of our study suggest that curcuminoid and boswellia formulations could be a valuable addition to the knee OA treatment regimens by relieving symptoms while reducing safety risks. The current body of evidence is not adequate in size or quality to make any meaningful clinical practice recommendations. Further research through large, high quality RCTs probably investigating the synergistic effect of these products with other OA treatments is warranted.”

Bannuru et al. · Authors' conclusion

Names both Boswellia and Curcumin Phytosome in its title.

Pharmacokinetic assessment of constituents of Boswellia serrata, pine bark extracts, curcumin in combination including methylsulfonylmethane in healthy volunteers.

The Journal of pharmacy and pharmacology · 2020 · PMID 31608447

Comparative StudyRandomized Controlled Trial

“These data suggest that interactions between the major constituents of this supplement combination are unlikely and therefore could be investigated to manage patients with osteoarthritis without significant concerns for possible pharmacokinetic interactions.”

Liu et al. · Authors' conclusion

Names both Boswellia and Curcumin Phytosome in its title.

A full-spectrum Boswellia serrata extract with enhanced bioavailability, and its co-delivered system with curcumin alleviate pain and stiffness associated with moderate spondylitis: a randomized double-blind, placebo-controlled, 3-arm study.

Frontiers in pharmacology · 2025 · PMID 40667507

105 participants

“Both F-BSE and C-BSE reduced pain and stiffness issues by day 14, which continued to progress through day 28. However, C-BSE demonstrated superior effects compared to F-BSE, indicating a synergistic anti-inflammatory and analgesic action when the full-spectrum Boswellia extract and curcumin are delivered as a water-soluble, non-covalent complex with enhanced bioavailability using the FenuMatĀ® delivery technology.”

Mamatha et al. · Authors' conclusion

Names both Boswellia and Curcumin Phytosome in its title.

Curcuminoids and Boswellia serrata extracts combination decreases tendinopathy symptoms: findings from an open-label post-observational study.

Current medical research and opinion · 2021 · PMID 33287570

Observational StudyHuman subjects

“HighlightsTendinopathy is a common disease representing 30% of all consultations with a general practitioner for musculoskeletal disorders.The combination of Curcuminoids and Boswelliaserrata extracts are efficient on tendinopathy symptoms in support of standard symptomatic treatments.The combination of Curcuminoids and B. Serrata extract is safe and can be administrated for at least 1 month in addition of analgesic and non-steroidal anti-inflammatory drugs.”

Henrotin et al. · From the abstract

Names Boswellia and Curcumin Phytosome together in an interaction, co-administration, or pharmacokinetic context.

Limitations

What this evidence cannot tell you.

Search-based evidence indexes have real limits, and it is worth being explicit about them:

How to read this page

A literature summary, not guidance.

NutriStack

Track what you actually take.

NutriStack is a free iPhone app for organising a supplement routine: what you take, when, and what the published record says about it. Its exploratory interaction checker covers Boswellia, Curcumin Phytosome, and several hundred other substances.

Log your routine, get reminders at the times you choose, and scan a label to add a product. The checker is a research and organisation tool, not a clinical decision aid.

NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.