Supplement × Prescription·a caution·Emerging evidence
Low magnesium can worsen neuromuscular irritability and arrhythmia risk when hypocalcemia occurs, but supplementation in kidney disease requires caution.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
What is happening. Low magnesium can worsen neuromuscular irritability and arrhythmia risk when hypocalcemia occurs, but supplementation in kidney disease requires caution.
Mechanism. Magnesium influences PTH secretion, neuromuscular excitability, and cardiac repolarization.
Recommendation. Correct magnesium only with clinician guidance, especially in dialysis or low kidney function.
Effect on the composite score
If both Cinacalcet and Magnesium Glycinate are in the same stack, this pair applies −5 to your Stack Score (per scored caution row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
Every claim on this page is cited. PMIDs link straight to PubMed.
Check your full routine
Drop your supplements and prescriptions into NutriStack and it runs every pair at once: every interaction, synergy, timing rule, and contraindication, each linked to its primary source.
NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.
NutriStack