What kind of interaction is it?

Synergy: a documented combination effect that is stronger or more useful than either substance taken alone.

Is this interaction backed by published research?

Yes. NutriStack lists 1 citation row for the Curcumin Phytosome + Tangeretin pair, each linking to PubMed by PMID where available. Full sourcing methodology at https://nutristackapp.com/methodology/interactions.

Supplement × Supplement·a synergy·Emerging evidence

Curcumin Phytosome + Tangeretin

Q: Can I take Curcumin Phytosome and Tangeretin together?

Yes. The combination of Curcumin Phytosome and Tangeretin produces a measurable benefit. Tangeretin and curcumin act through complementary anti-inflammatory and antioxidant pathways and may provide additive support against low-grade inflammation.

Q: How does this affect a NutriStack Stack Score?

+2 to your Stack Score per scored synergy row.

Synergy Emerging evidence

Tangeretin and curcumin act through complementary anti-inflammatory and antioxidant pathways and may provide additive support against low-grade inflammation.

Supplement × Supplement

Open the interaction checker → Read the methodology

From the database

What the row says.

Every entry follows the same shape: what is happening, the mechanism, and the recommendation.

Substances

Curcumin Phytosome and Tangeretin

Pair type

Synergy

Evidence

Emerging

Source citations

Scope

Supplement × Supplement

Last verified

June 4, 2026

SynergyEmerging evidence

What is happening. Tangeretin and curcumin act through complementary anti-inflammatory and antioxidant pathways and may provide additive support against low-grade inflammation.

Mechanism. Curcumin and tangeretin both suppress NF-kB signaling and pro-inflammatory cytokines while activating Nrf2-mediated antioxidant defenses, producing partly additive effects.

Recommendation. Reasonable to combine for anti-inflammatory and metabolic goals; take with food. No separation needed, though both can modulate drug metabolism so review concurrent medications.

Stack Score

How it moves the number.

Effect on the composite score

If both Curcumin Phytosome and Tangeretin are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).

The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.

Sources

Sources, by evidence tier.

Every claim on this page is cited. PMIDs link straight to PubMed.

Reference material

1Li S, et al. Chemistry and health effects of polymethoxyflavones and hydroxylated polymethoxyflavones. Journal of Functional Foods. 2009.Needs sourceNo link

Check your full routine

One pair was the worked example.

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Open the interaction checker → Browse the research index