From the databaseWhat the row says.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
Scope
Supplement × Supplement
Last verified
June 4, 2026
SynergyEmerging evidence
What is happening. Tangeretin and omega-3 fish oil work through complementary mechanisms to improve lipid profiles and reduce vascular inflammation.
Mechanism. Omega-3 fatty acids lower triglycerides and yield anti-inflammatory resolvins, while tangeretin reduces hepatic apolipoprotein B secretion and NF-kB-mediated inflammation, giving additive lipid and vascular benefit in preclinical models.
Recommendation. Reasonable to combine for cardiometabolic support; take with food, no separation required.
Stack Score
How it moves the number.
Effect on the composite score
If both Fish Oil and Tangeretin are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
SourcesSources, by evidence tier.
Every claim on this page is cited. PMIDs link straight to PubMed.
Reference material
1- 1Kurowska EM, Manthey JA. Hypolipidemic effects and absorption of citrus polymethoxylated flavones in hamsters with diet-induced hypercholesterolemia. Journal of Agricultural and Food Chemistry. 2004.Needs sourceNo link