What kind of interaction is it?

Caution: an interaction that may reduce efficacy or raise side-effect risk and warrants monitoring.

Is this interaction backed by published research?

Yes. NutriStack lists 1 citation row for the Ellagic Acid + Green Tea Extract pair, each linking to PubMed by PMID where available. Full sourcing methodology at https://nutristackapp.com/methodology/interactions.

Supplement × Supplement·a caution·Emerging evidence

Ellagic Acid + Green Tea Extract

Q: Can I take Ellagic Acid and Green Tea Extract together?

Possibly, but with caution. Ellagic Acid and Green Tea Extract have a documented caution-tier interaction. Both ellagic acid (and its ellagitannin-rich source extracts) and green tea extract are concentrated polyphenols. Stacking multiple high-dose polyphenol extracts increases cumulative tannin/catechin load, which can compound mineral malabsorption and, in the case of high-dose green tea catechins, raises the theoretical hepatotoxicity burden.

Q: How does this affect a NutriStack Stack Score?

-5 to your Stack Score per scored caution row.

Caution Emerging evidence

Both ellagic acid (and its ellagitannin-rich source extracts) and green tea extract are concentrated polyphenols. Stacking multiple high-dose polyphenol extracts increases cumulative tannin/catechin load, which can compound mineral malabsorption and, in the case of high-dose green tea catechins, raises the theoretical hepatotoxicity burden.

Supplement × Supplement

Open the interaction checker → Read the methodology

From the database

What the row says.

Every entry follows the same shape: what is happening, the mechanism, and the recommendation.

Substances

Ellagic Acid and Green Tea Extract

Pair type

Caution

Evidence

Emerging

Source citations

Scope

Supplement × Supplement

Last verified

June 4, 2026

CautionEmerging evidence

What is happening. Both ellagic acid (and its ellagitannin-rich source extracts) and green tea extract are concentrated polyphenols. Stacking multiple high-dose polyphenol extracts increases cumulative tannin/catechin load, which can compound mineral malabsorption and, in the case of high-dose green tea catechins, raises the theoretical hepatotoxicity burden.

Mechanism. Additive polyphenol/tannin burden increases gut mineral chelation; concentrated green tea catechins (notably EGCG) carry a dose-dependent idiosyncratic hepatotoxicity signal that combined polyphenol loading does not relieve.

Recommendation. Avoid stacking several high-dose polyphenol extracts at maximal doses. Keep green tea extract within recommended limits, take with food, and watch for GI upset. Separate both from iron and other mineral supplements.

Stack Score

How it moves the number.

Effect on the composite score

If both Ellagic Acid and Green Tea Extract are in the same stack, this pair applies −5 to your Stack Score (per scored caution row).

The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.

Sources

Sources, by evidence tier.

Every claim on this page is cited. PMIDs link straight to PubMed.

Reference material

1Hu J, Webster D, Cao J, Shao A. The safety of green tea and green tea extract consumption in adults - Results of a systematic review. Regulatory Toxicology and Pharmacology. 2018.Needs sourceNo link

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