NutriStack
Enoxaparin and Garlic Extract, a caution.
Concentrated garlic supplements inhibit platelet aggregation through allicin and related compounds and have been linked to perioperative bleeding. Added to enoxaparin's anti-factor Xa activity, garlic supplements can additively raise bleeding risk. Dietary garlic is not a concern.
One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.
From the interaction database
What the row says.
Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.
At a glance
- Substances
- Enoxaparin and Garlic Extract
- Pair type
- Caution
- Evidence (highest tier)
- Emerging
- Source citations
- 2 sources
- Stack Score effect
- −5 to your Stack Score (per scored caution row).
- Scope
- Supplement × Prescription
- Last verified
- May 30, 2026
Caution · Emerging evidence
Caution
What is happening. Concentrated garlic supplements inhibit platelet aggregation through allicin and related compounds and have been linked to perioperative bleeding. Added to enoxaparin's anti-factor Xa activity, garlic supplements can additively raise bleeding risk. Dietary garlic is not a concern.
Mechanism. Allicin and related organosulfur compounds inhibit platelet thromboxane synthesis, modify platelet membrane properties, and reduce calcium signalling, lowering aggregation. This is additive to enoxaparin's anti-factor Xa effect.
Recommendation. Avoid concentrated garlic supplements while on enoxaparin, especially if you are receiving treatment doses or are perioperative. Stop garlic supplements at least 7 days before any planned surgery. Cooking with garlic is fine.
Stack Score
How this pair moves the number.
Effect on the composite score
If both Enoxaparin and Garlic Extract are in the same stack, this pair applies −5 to your Stack Score (per scored caution row).
The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.
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