NSTK · 01.2026Independent supplement reference
NutriStack
Edition 1.0Updated August 1, 2026

Supplement × Supplement·Evidence index

Black Seed Oil and Garlic Extract: what the published research says

PubMed indexes 8 records that name Black Seed Oil and Garlic Extract together, either in the title or in an interaction, co-administration, or pharmacokinetic context. Each one is listed below with its study design and, where the abstract states one, the authors’ own conclusion, quoted and linked. This page reports that literature. It does not tell you whether to combine them.

Read this first

An evidence index, not guidance.

Every statement below is attributed to a named, dated, linked source.

This page lists published research relevant to Black Seed Oil and Garlic Extract. It deliberately does not state whether the combination is safe, whether it interacts, in which direction, at what dose, or how far apart to take them.

The research

8 studies naming Black Seed Oil and Garlic Extract.

Strongest relevance first: papers naming both substances in the title, then human trials and systematic reviews.

Effect of Allium sativum and Nigella sativa on alleviating aluminum toxicity state in the albino rats.

Frontiers in veterinary science · 2022 · PMID 36524230

“In addition, there were protective effects for Allium sativum and Nigella sativa against aluminum on serum creatinine, urea, ALT, and AST concentrations. The present study concluded that supplementation with Allium sativum or Nigella sativa or their combination could reduce aluminum toxicity and return the liver, kidney, and testes to normal.”

Abdel Ghfar et al. · From the abstract

Names both Black Seed Oil and Garlic Extract in its title.

Evaluation of Antischistosomal Activities of Crude Aqueous Extracts of Artemisia annua, Nigella sativa, and Allium sativum against Schistosoma mansoni in Hamsters.

BioMed research international · 2022 · PMID 35313628

Animal study

“In vivo study was accomplished on the hamster's tissue after exposing it to doses of the plants' extracts with different concentrations; it showed the presence of calcifications and damage to the worm eggs in the liver and spleen, as well as reducing the size of granulomas. After conducting many confirmatory studies Artemisia annua extract can be used as an effective and safe treatment for Schistosoma disease.”

Fadladdin · From the abstract

Names both Black Seed Oil and Garlic Extract in its title.

Deodorant Activity of Black Cumin Seed Essential Oil against Garlic Organosulfur Compound.

Biomolecules · 2021 · PMID 34944518

Human subjects

“As a result, these substances were identified as different allyl mercaptan adducts to dihydrothymoquinone. This chemical reaction was presumed to play a key role in the deodorant activity of black cumin seed essential oil.”

Yoshioka et al. · From the abstract

Names both Black Seed Oil and Garlic Extract in its title.

Limitations

What this evidence cannot tell you.

Search-based evidence indexes have real limits, and it is worth being explicit about them:

NutriStack

Track what you actually take.

NutriStack is a free iPhone app for organising a supplement routine: what you take, when, and what the published record says about it. Its exploratory interaction checker covers Black Seed Oil, Garlic Extract, and several hundred other substances.

The checker is a research and organisation tool, not a clinical decision aid, and its per-pair assessments are excluded from search until they pass claim-level review.

NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.