Supplement × Supplement·Evidence index
PubMed indexes 8 records that name Black Seed Oil and Fenugreek together, either in the title or in an interaction, co-administration, or pharmacokinetic context. Each one is listed below with its study design and, where the abstract states one, the authors’ own conclusion, quoted and linked. This page reports that literature. It does not tell you whether to combine them.
Every statement below is attributed to a named, dated, linked source.
This page lists published research relevant to Black Seed Oil and Fenugreek. It deliberately does not state whether the combination is safe, whether it interacts, in which direction, at what dose, or how far apart to take them.
Strongest relevance first: papers naming both substances in the title, then human trials and systematic reviews.
“N. sativa/fenugreek supplemented chapatis present a safe and seamless dietary modification to address cardiometabolic risk.”
Names both Black Seed Oil and Fenugreek in its title.
Names both Black Seed Oil and Fenugreek in its title.
“sativa and T. foenum-graecum can serve as novel, environmentally friendly bioinsecticides.”
Names both Black Seed Oil and Fenugreek in its title.
Names both Black Seed Oil and Fenugreek in its title.
Names both Black Seed Oil and Fenugreek in its title.
“The combination of investigated herbs and MT had a beneficial effect on hypertension. However, the concurrent administration of drugs, particularly those predominantly cleared through CYP450 2D6-catalyzed metabolism, with the three investigated herbs should be considered with caution.”
Names both Black Seed Oil and Fenugreek in its title.
“Results of pharmacodynamics and pharmacokinetics studies suggested that simultaneous administration of fenugreek or N. sativa with amlodipine improved the pharmacological response of amlodipine in hypertensive rats, though there was no remarkable change in pharmacokinetic parameters (Cmax, Kel, elimination t1/2, and AUC0-t).”
Names both Black Seed Oil and Fenugreek in its title.
“Sativa & losartan and T. Foenum-graecum & losartan could take place on concurrent administration; consequently, the dose of losartan may need to be accustomed when they are utilized simultaneously.”
Names both Black Seed Oil and Fenugreek in its title.
Search-based evidence indexes have real limits, and it is worth being explicit about them:
NutriStack is a free iPhone app for organising a supplement routine: what you take, when, and what the published record says about it. Its exploratory interaction checker covers Black Seed Oil, Fenugreek, and several hundred other substances.
The checker is a research and organisation tool, not a clinical decision aid, and its per-pair assessments are excluded from search until they pass claim-level review.
NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.
